Results 81 to 90 of about 9,925,647 (298)
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Error correction during DNA replication
, 2012 DNA polymerase (DNAP) is a dual-purpose enzyme that plays two opposite roles in two different situations during DNA replication. It plays its normal role as a {\it polymerase} catalyzing the elongation of a new DNA molecule by adding a monomer.
Chowdhury, Debashish, Sharma, Ajeet K.
core +1 more source
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Molecular Oncology, EarlyView.The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
L'error en els aparells com a possibilitat estètica
Artnodes, 2012 L'error sembla que és el que s'interposa entre l'ésser ideal i el real. Un esdeveniment, un No-ésser que transforma i deforma l'Ésser. En les tècniques, tecnologies, suports i mitjans audiovisuals es mira de suprimir; tanmateix, hi ha una possibilitat ...
Alejandro Schianchi
doaj +1 more source
Quantum Convolutional Error Correction Codes
, 1998 I report two general methods to construct quantum convolutional codes for quantum registers with internal $N$ states. Using one of these methods, I construct a quantum convolutional code of rate 1/4 which is able to correct one general quantum error for ...
A. Dholakia +19 more
core +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Известия высших учебных заведений: Нефть и газ, 2016 This article considers the problems of estimation of the structural model verification based on the results of the well horizontal section drilling. The method of estimation by standard criteria of the structure confirmation is presented as well as the ...
R. M. Bembel, I. A. Schetinin
doaj +1 more source
Optimal Networks from Error Correcting Codes
, 2013 To address growth challenges facing large Data Centers and supercomputing clusters a new construction is presented for scalable, high throughput, low latency networks.
Tomic, Ratko V.
core +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source