Results 81 to 90 of about 10,243,879 (347)
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Operating during the COVID-19 pandemic: How to reduce medical error [PDF]
, 2020 Ricky Ellis +2 more
openalex +1 more source
Good Quantum Error-Correcting Codes Exist
, 1995 A quantum error-correcting code is defined to be a unitary mapping (encoding) of k qubits (2-state quantum systems) into a subspace of the quantum state space of n qubits such that if any t of the qubits undergo arbitrary decoherence, not necessarily ...
Calderbank, A. R., Shor, Peter W.
core +3 more sources
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Multiwave validation sampling for error‐prone electronic health records [PDF]
, 2022 Bryan E. Shepherd +8 more
openalex +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Acta Médica Costarricense, 2008 En todas las actuaciones de los seres humanos, los errores son una realidad innegable. Por ser el ejercicio de la medicina algo que afecta directamente a las personas, este tema es uno de los más controvertidos, tanto en el nivel profesional como en los medios de comunicación, que siempre están ávidos de noticias impactantes y las destacan con ...
openaire +4 more sources
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Известия высших учебных заведений: Нефть и газ, 2016 This article considers the problems of estimation of the structural model verification based on the results of the well horizontal section drilling. The method of estimation by standard criteria of the structure confirmation is presented as well as the ...
R. M. Bembel, I. A. Schetinin
doaj +1 more source
Minimum error discrimination of Pauli channels
, 2005 We solve the problem of discriminating with minimum error probability two given Pauli channels. We show that, differently from the case of discrimination between unitary transformations, the use of entanglement with an ancillary system can strictly ...
Aharonov D Kitaev A Nisan N +11 more
core +2 more sources