Results 101 to 110 of about 7,381,056 (283)
Backward error analysis for multisymplectic discretizations of Hamiltonian PDEs
, 2004 Several recently developed multisymplectic schemes for Hamiltonian PDEs have been shown to preserve associated local conservation laws and constraints very well in long time numerical simulations.
Islas, Alvaro L., Schober, Constance M.
core +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Efficient Algorithms and Error Analysis for the Modified Nystrom Method [PDF]
, 2014 Many kernel methods suffer from high time and space complexities and are thus prohibitive in big-data applications. To tackle the computational challenge, the Nystr\"om method has been extensively used to reduce time and space complexities by sacrificing
Wang, Shusen, Zhang, Zhihua
core
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
تحليل الأخطاء الكتابية الإملائية في تعليمات المنتجات الإندونيسية
Okara: Jurnal Bahasa dan Sastra, 2017 This article describes errors of writing found in ingredients of Indonesian products which are written in Arabic, for example ingredients of foods or snacks based on imla’ and non-imla’ perspective.
Achmad Muhlis, Umi Alifatil Azizah
doaj +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Confidence Estimation for Machine Learning-Based Quantitative Photoacoustics
Journal of Imaging, 2018 In medical applications, the accuracy and robustness of imaging methods are of crucial importance to ensure optimal patient care. While photoacoustic imaging (PAI) is an emerging modality with promising clinical applicability, state-of-the-art approaches
Janek Gröhl +3 more
doaj +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Coordinating sentence composition with error correction: A multilevel analysis
Journal of Writing Research, 2011 Error analysis involves detecting and correcting discrepancies between the 'text produced so far' (TPSF) and the writer's mental representation of what the text should be.
Van Waes, L., De Maeyer, S., Leijten, M.
doaj