Results 161 to 170 of about 31,673,086 (385)

ITGAV and SMAD4 influence the progression and clinical outcome of pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
In SMAD4‐positive pancreatic ductal adenocarcinoma (PDAC), integrin subunit alpha V (ITGAV) activates latent TGF‐β, which binds to the TGF‐β receptor and phosphorylates SMAD2/3. The activated SMAD2/3 forms a complex with SMAD4, and together they translocate to the nucleus, modulating gene expression to promote proliferation, migration, and invasion. In
Daniel K. C. Lee   +9 more
wiley   +1 more source

Analysis of round-off errors

open access: yesApplied Mathematics Letters, 1992
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +2 more sources

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

open access: yesMolecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima   +6 more
wiley   +1 more source

Hamiltonian conserved Crank-Nicolson schemes for a semi-linear wave equation based on the exponential scalar auxiliary variables approach

open access: yesElectronic Research Archive
The keys to constructing numerical schemes for nonlinear partial differential equations are accuracy, handling of the nonlinear terms, and physical properties (energy dissipation or conservation). In this paper, we employ the exponential scalar auxiliary
Huanhuan Li   +4 more
doaj   +1 more source

Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation

open access: yesMolecular Oncology, EarlyView.
Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides   +13 more
wiley   +1 more source

Orthographic Processing of Spanish as a Heritage Language in Gibraltar: The Role of Interactional Context in Interference Control

open access: yesLanguages
Despite the increase in studies on Spanish as a heritage language (SHL), few focus on spelling, with research limited to the U.S. According to the adaptive control hypothesis, language production is governed by control processes, which adapt to the ...
Alicia Mariscal
doaj   +1 more source

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