Results 151 to 160 of about 5,618,804 (375)

Identification of inhibitors of the Salmonella FraB deglycase, a drug target

FEBS Open Bio, EarlyView.
A high‐throughput screen was used to identify inhibitors of Salmonella FraB, a drug target. Characterization of top hits (identified after an additional counter screen) revealed that some triazolidines, thiadiazolidines, and triazolothiadiazoles are mixed‐type inhibitors of FraB.
Jamison D. Law, Yuan Gao, Sravya Kovvali, Pankajavalli Thirugnanasambantham, Vicki H. Wysocki, Brian M. M. Ahmer, Venkat Gopalan   +6 more
wiley   +1 more source

PREMIER - PRobabilistic Error-correction using Markov Inference in Errored Reads [PDF]

, 2013
In this work we present a flexible, probabilistic and reference-free method of error correction for high throughput DNA sequencing data. The key is to exploit the high coverage of sequencing data and model short sequence outputs as independent ...
Dorman, Karin, Ramamoorthy, Aditya, Ramamoorthy, Aditya, Song, Zhao, Yin, Xin   +4 more
core   +3 more sources

Quantum error correction via robust probe modes

, 2005
We propose a new scheme for quantum error correction using robust continuous variable probe modes, rather than fragile ancilla qubits, to detect errors without destroying data qubits.
Fumiko Yamaguchi, Kae Nemoto, M. A. Nielsen, P. W. Shor, William J. Munro   +4 more
core   +1 more source

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

FEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi, Xin Gao, Takashi Gojobori   +2 more
wiley   +1 more source

Development of a Drosophila cell-based error correction assay

Frontiers in Oncology, 2013
Accurate transmission of the genome through cell division requires microtubules from opposing spindle poles to interact with protein super-structures called kinetochores that assemble on each sister chromatid.
Jeffrey D. Salemi, Philip T. McGilvray, Thomas J. Maresca, Thomas J. Maresca   +3 more
doaj   +1 more source

Mapping Hsp104 interactions using cross‐linking mass spectrometry

FEBS Open Bio, EarlyView.
This study examines how cross‐linking mass spectrometry can be utilized to analyze ATP‐induced conformational changes in Hsp104 and its interactions with substrates. We developed an analytical pipeline to distinguish between intra‐ and inter‐subunit contacts within the hexameric homo‐oligomer and discovered contacts between Hsp104 and a selected ...
Kinga Westphal, Karolina Michalska, Andrzej Joachimiak, Lukasz A. Joachimiak   +3 more
wiley   +1 more source

Adaptively correcting quantum errors with entanglement [PDF]

arXiv, 2011
Contrary to the assumption that most quantum error-correcting codes (QECC) make, it is expected that phase errors are much more likely than bit errors in physical devices. By employing the entanglement-assisted stabilizer formalism, we develop a new kind of error-correcting protocol which can flexibly trade error correction abilities between the two ...
arxiv  

Perturbative Quantum Error Correction [PDF]

Physical Review Letters, 2011
We derive simple necessary and sufficient conditions under which a quantum channel obtained from an arbitrary perturbation from the identity can be reversed on a given code to the lowest order in fidelity. We find the usual Knill-Laflamme conditions applied to a certain operator subspace which, for a generic perturbation, is generated by the Lindblad ...
openaire   +5 more sources

Research on business English grammar detection system based on LSTM model

Journal of Intelligent Systems
In order to solve the problems that the current English grammar correction algorithms are not effective, the error correction ability is limited, and the error correction accuracy needs to be improved, this study proposes an automatic grammar correction ...
Huang Xiaojie
doaj   +1 more source

An Introduction to Error-Correcting Codes: From Classical to Quantum [PDF]

arXiv, 2006
This report surveys quantum error-correcting codes. As Preskill claimed, 21st century would be the golden age of quantum error correction. Quantum channels behave differently from classical channels, so researchers face difficulties in developing robust quantum codes. Fortunately, the classical error control methods have been well developed.
arxiv