Results 41 to 50 of about 634 (212)
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Construction of LDPC codes for higher burst-error detecting
Tongxin xuebao, 2007 The coding of LDPC codes is focused on several aspects: high error-correction,low coding complexity and so on.All the construction methods do not give much consideration on hamming-distance and its distribution because of computation complexity.A ...
YAO Chun-guang1 +3 more
doaj +2 more sources
Codes correcting restricted errors [PDF]
Designs, Codes and Cryptography, 2018 We study the largest possible length $B$ of $(B-1)$-dimensional linear codes over $\mathbb{F}_q$ which can correct up to $t$ errors taken from a restricted set $\mathcal{A}\subseteq \mathbb{F}_q^*$. Such codes can be applied to multilevel flash memories.
Igor E. Shparlinski, Arne Winterhof
openaire +2 more sources
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Energy-Efficient Channel Coding Strategy for Underwater Acoustic Networks
Sensors, 2017 Underwater acoustic networks (UAN) allow for efficiently exploiting and monitoring the sub-aquatic environment. These networks are characterized by long propagation delays, error-prone channels and half-duplex communication. In this paper, we address the
Grasielli Barreto +7 more
doaj +1 more source
IEEE Access, 2020 In digital communication systems, error correction codes are used to recover data that has been disturbed in a noisy environment. Convolutional code is a commonly used error correction code. In non-cooperative communication systems, it is very meaningful
Yong Ding, Zhiping Huang, Jing Zhou
doaj +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source