Results 71 to 80 of about 1,470,732 (345)

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

High-Precision Calibration Technology and Experimental Verification for Dual-Axis Laser Communication Systems

Sensors
With the continuous improvement of remote sensing satellite resolution, laser communication technology has gained significant traction. The pointing accuracy of ground-based laser communication terminals is critical for the stability of satellite–ground ...
Wenyan Li, Xiaolei Zhang, Lei Zhang, Xiang Wei, Guoxi Luo, Peng Zhang, Zhipeng Xue   +6 more
doaj   +1 more source

On the problem of non-zero word error rates for fixed-rate error correction codes in continuous variable quantum key distribution

New Journal of Physics, 2017
The maximum operational range of continuous variable quantum key distribution protocols has shown to be improved by employing high-efficiency forward error correction codes.
Sarah J Johnson, Andrew M Lance, Lawrence Ong, Mahyar Shirvanimoghaddam, T C Ralph, Thomas Symul   +5 more
doaj   +1 more source

Correcting errors in seasonal Arctic sea ice prediction of Earth system models with machine learning [PDF]

The Cryosphere
While Earth system models are essential for seasonal Arctic sea ice prediction, they often exhibit significant errors that are challenging to correct.
Z. He, Z. He, Z. He, Y. Wang, J. Brajard, X. Wang, X. Wang, Z. Shen, Z. Shen   +8 more
doaj   +1 more source

Context-sensitive Spelling Correction Using Google Web 1T 5-Gram Information

, 2012
In computing, spell checking is the process of detecting and sometimes providing spelling suggestions for incorrectly spelled words in a text. Basically, a spell checker is a computer program that uses a dictionary of words to perform spell checking. The
Alwani, Mohammad, Bassil, Youssef
core   +2 more sources

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

English grammar intelligent error correction technology based on the n-gram language model

Journal of Intelligent Systems
With the development of the Internet, the number of electronic texts has increased rapidly. Automatic grammar error correction technology is an effective safeguard measure for the quality of electronic texts.
Xiao Fan, Yin Shehui
doaj   +1 more source

Improving Angular Accuracy of a Scanning Mirror Based on Error Modeling and Correction

Sensors, 2019
Scanning mirrors appear to be key components in optoelectronic systems for line-of-sight (LOS) stabilization. For improving the angular accuracy of a scanning mirror based on the eddy current displacement sensor measurement, an angular error-correction ...
Yue Fan, Wenli Ma, Ping Jiang, Jinlong Huang, Kewei Chen, Nian Pan   +5 more
doaj   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

EDCEW-LLM: Error detection and correction in English writing: A large language model-based approach

Alexandria Engineering Journal
This study investigates the use of large language models (LLMs) for error detection and correction in English writing (EDCEW), focusing on the challenges of overcorrection and pedagogical feedback.
Jin Wang
doaj   +1 more source