Results 141 to 150 of about 1,041,335 (309)

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Singular Value Decomposition (SVD) Method for LiDAR and Camera Sensor Fusion and Pattern Matching Algorithm

Sensors
LiDAR and camera sensors are widely utilized in autonomous vehicles (AVs) and robotics due to their complementary sensing capabilities—LiDAR provides precise depth information, while cameras capture rich visual context.
Kaiqiao Tian, Meiqi Song, Ka C. Cheok, Micho Radovnikovich, Kazuyuki Kobayashi, Changqing Cai   +5 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Efficient parallel MAP timing recovery algorithm for TDS-OFDM systems

Dianxin kexue, 2018
According to the problems of the existing timing recovery algorithm with the time-domain orthogonal frequency division multiplexing (TDS-OFDM) modulation in the wireless multimedia transmissions of 5G communications,such as slow processing speed and big ...
Yangguang LI, Jianrong BAO, Bin JIANG, Chao LIU   +3 more
doaj  

Residue-level error detection in cryoelectron microscopy models. [PDF]

Structure, 2023
Reggiano G, Lugmayr W, Farrell D, Marlovits TC, DiMaio F.   +4 more
europepmc   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Simple and Accurate Error Probability Evaluation of Multiple-Input–Multiple-Output Systems Using Optimum Linear Combining [PDF]

, 2010
This correspondence motivates simple and accurate evaluation of the error probability of multiantenna multiple-input–multipleoutput (MIMO) systems using optimum linear combining (OLC).
Yang, Lie-Liang, Yang, Wei
core  

Online Language Education: Principles of Creating a Marked Corpus of Learners’ Mistakes

Виртуальная коммуникация и социальные сети
Today, academic corpora are a matter of great interest to many linguists. The article examines the importance of academic corpora in modern linguistics and pedagogy as a tool for identifying typical errors in the speech of foreign language students. They
Iuliia S. Vinogradova, Igor V. Ilchenko, Polina S. Shiriaeva, Maria S. Gorina   +3 more
doaj   +1 more source

Deep Learning-Based Boolean, Time Series, Error Detection, and Predictive Analysis in Container Crane Operations

Algorithms
Deep learning is crucial in marine logistics and container crane error detection, diagnosis, and prediction. A novel deep learning technique using Long Short-Term Memory (LSTM) detected and anticipated errors in a system with imbalanced data.
Amruta Awasthi, Lenka Krpalkova, Joseph Walsh   +2 more
doaj   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source