Digital twins to accelerate target identification and drug development for immune‐mediated disorders
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Enhancing laparoscopic surgery training: a comparative study of traditional models and automated error detection system. [PDF]
Luo Y +11 more
europepmc +1 more source
Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
Train-Time and Test-Time Computation in Large Language Models for Error Detection and Correction in Electronic Medical Records: A Retrospective Study. [PDF]
Cai Q +5 more
europepmc +1 more source
Acute Exercise Improves Inhibitory Control but Not Error Detection in Male Violent Perpetrators: An ERPs Study With the Emotional Stop Signal Task. [PDF]
Yu CC +4 more
europepmc +1 more source
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley +1 more source
EzSkiROS: enhancing robot skill composition with embedded DSL for early error detection. [PDF]
Rizwan M +4 more
europepmc +1 more source
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
An assessment of ChatGPT in error detection for thyroid ultrasound reports: A comparative study with ultrasound physicians. [PDF]
Xu Z +9 more
europepmc +1 more source
Automatic Detection of Grammatical Errors in English Verbs Based on RNN Algorithm: Auxiliary Objectives for Neural Error Detection Models. [PDF]
He Y.
europepmc +1 more source

