Results 61 to 70 of about 2,569,797 (292)

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Context-sensitive Spelling Correction Using Google Web 1T 5-Gram Information

open access: yes, 2012
In computing, spell checking is the process of detecting and sometimes providing spelling suggestions for incorrectly spelled words in a text. Basically, a spell checker is a computer program that uses a dictionary of words to perform spell checking. The
Alwani, Mohammad, Bassil, Youssef
core   +2 more sources

On basis variables for efficient error detection [PDF]

open access: yes, 2018
The development of dependable software invariably entails the design and location of error detection mechanisms. This software artefact type captures predicates over program variables in order to facilitate error detection.
Fairbrother, Jake, Leeke, Matthew
core   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Neuroadaptive haptics: a proof-of-concept comparing reinforcement learning from explicit ratings and neural signals for adaptive XR systems

open access: yesFrontiers in Virtual Reality
IntroductionNeuroadaptive technology provides a promising path to enhancing immersive extended reality (XR) experiences by dynamically tuning multisensory feedback to user preferences. This study introduces a novel system employing reinforcement learning
Lukas Gehrke   +3 more
doaj   +1 more source

Error Detection in a Large-Scale Lexical Taxonomy

open access: yesInformation, 2020
Knowledge base (KB) is an important aspect in artificial intelligence. One significant challenge faced by KB construction is that it contains many noises, which prevent its effective usage.
Yinan An, Sifan Liu, Hongzhi Wang
doaj   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Investigation of an Optimum Detection Scheme for a Star-Field Mapping System [PDF]

open access: yes, 1970
An investigation was made to determine the optimum detection scheme for a star-field mapping system that uses coded detection resulting from starlight shining through specially arranged multiple slits of a reticle.
Aldridge, M. D., Credeur, L.
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

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