Results 61 to 70 of about 1,205,694 (316)

A cellular system to study responses to a collision between the transcription complex and a protein‐bound nick in the DNA template

FEBS Letters, EarlyView.
We present the cellular transcription‐coupled Flp‐nick system allowing the introduction of a Top1‐mimicking cleavage complex (Flpcc) at a Flp recognition target site within a controllable LacZ gene. LacZ transcription leads to the collision of RNA polymerase II (RNAPII) with Flpcc, and this causes RNAPII stalling, ubiquitination, and degradation.
Petra Herring, Morten Roedgaard, Camilla Myrup Holst, Helene Christensen, Birgitta R. Knudsen, Lotte Bjergbaek, Anni Hangaard Andersen   +6 more
wiley   +1 more source

Knowledge Error Detection via Textual and Structural Joint Learning

Big Data Mining and Analytics
Knowledge graphs are essential tools for representing real-world facts and finding wide applications in various domains. However, the process of constructing knowledge graphs often introduces noises and errors, which can negatively impact the performance
Xiaoyu Wang, Xiang Ao, Fuwei Zhang, Zhao Zhang, Qing He   +4 more
doaj   +1 more source

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

FEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke, Izadora Volpato Rossi, Marcel I. Ramirez   +2 more
wiley   +1 more source

Beyond error detection

Nordic Journal of Science and Technology Studies
This study explores the performative role of checklists in enhancing the quality of digital forensic analysis and reporting within the criminal justice system.
Nina Sunde
doaj   +1 more source

Speech Synthesis in the Translation Revision Process: Evidence from Error Analysis, Questionnaire, and Eye-Tracking

Informatics, 2019
Translation revision is a relevant topic for translator training and research. Recent technological developments justify increased focus on embedding speech technologies—speech synthesis (text-to-speech) and speech recognition (speech-to-text ...
Dragoş Ciobanu, Valentina Ragni, Alina Secară   +2 more
doaj   +1 more source

Concurrent Classifier Error Detection (CCED) in Large Scale Machine Learning Systems [PDF]

IEEE Transactions on Reliability, 2024, 2023
The complexity of Machine Learning (ML) systems increases each year, with current implementations of large language models or text-to-image generators having billions of parameters and requiring billions of arithmetic operations. As these systems are widely utilized, ensuring their reliable operation is becoming a design requirement.
arxiv  

STAT3 expression is reduced in cardiac pericytes in HFpEF and its loss reduces cellular adhesion and induces pericyte senescence

FEBS Letters, EarlyView.
Heart failure with preserved ejection fraction (HFpEF) accounts for half of the heart failure cases. It is characterised by microvascular dysfunction, associated with reduced pericyte coverage and diminished STAT3 expression in pericytes. Loss of STAT3 impairs pericyte adhesion, promotes senescence, and activates a pro‐fibrotic gene program.
Leah Rebecca Vanicek, Ariane Fischer, Mariano Ruz Jurado, Anita Tamiato, Tara Procida‐Kowalski, Jochen Wilhelm, Dennis Hecker, Maximilian Merten, Felicitas Escher, Badder Kattih, Valentina Puntmann, David John, Marcel H. Schulz, Eike Nagel, Stefanie Dimmeler, Guillermo Luxán   +15 more
wiley   +1 more source

Performance Monitoring Applied to System Supervision

Frontiers in Human Neuroscience, 2017
Nowadays, automation is present in every aspect of our daily life and has some benefits. Nonetheless, empirical data suggest that traditional automation has many negative performance and safety consequences as it changed task performers into task ...
Bertille Somon, Bertille Somon, Aurélie Campagne, Arnaud Delorme, Arnaud Delorme, Bruno Berberian   +5 more
doaj   +1 more source

Protonophore activity of short‐chain fatty acids induces their intracellular accumulation and acidification

FEBS Letters, EarlyView.
The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang, Frans Bianchi, Geert van den Bogaart   +2 more
wiley   +1 more source

Editors’ Choice—Review—Sensor-Based and Computational Methods for Error Detection and Correction in 3D Printing

ECS Sensors Plus
Additive manufacturing in the realm of 3D printing has transformed the manufacturing sector, providing unmatched freedom in design and rapid prototyping abilities.
Prateek Mehta, Mubarak A. Mujawar, Samantha Lafrance, Shonda Bernadin, Daniel Ewing, Shekhar Bhansali   +5 more
doaj   +1 more source