Results 71 to 80 of about 8,753,061 (307)

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin   +2 more
wiley   +1 more source

A Comprehensive Database and Smart-Learning Framework for Monitoring Failure Risk Factors, Maintenance, and Protection in Electrical Networks

open access: yesEnergies
Electrical power systems are exposed to interacting electrical, thermal, environmental, and resource-related faults such as leakage current, voltage and frequency deviations, overcurrent, harmonic distortion, phase-sequence error, humidity, fire, wind ...
Anwr Abd S. Elasyri   +2 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Error Detection in a Large-Scale Lexical Taxonomy

open access: yesInformation, 2020
Knowledge base (KB) is an important aspect in artificial intelligence. One significant challenge faced by KB construction is that it contains many noises, which prevent its effective usage.
Yinan An, Sifan Liu, Hongzhi Wang
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Optimising Solar Power Plant Reliability Using Neural Networks for Fault Detection and Diagnosis

open access: yesElektronika ir Elektrotechnika
This study introduces an intelligent method to monitor grid-connected solar power stations, focussing on detecting problems in their energy output through the use of artificial neural networks (ANN).
Mohammed Bouzidi   +3 more
doaj   +1 more source

The Effect of Static and Dynamic Visual Stimulations on Error Detection Based on Error-Evoked Brain Responses

open access: yesSensors, 2020
Error-related potentials (ErrPs) have provided technical support for the brain-computer interface. However, different visual stimulations may affect the ErrPs, and furthermore, affect the error recognition based on ErrPs.
Rui Xu   +4 more
doaj   +1 more source

Home - About - Disclaimer - Privacy