Results 101 to 110 of about 3,900,571 (293)

Finite Element Approximation of Variational Inequalities: An Algorithmic Approach

open access: yesSultan Qaboos University Journal for Science, 2018
In this paper, we introduce a new method to analyze the convergence of the standard finite element method for elliptic variational inequalities with noncoercive operators (VI).
Messaoud Boulbrachene
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Contribution to error estimate [PDF]

open access: yes, 1982
The error estimate of an approximate solution to a nonlinear ordinary differential equations of the second order is obtained. The differential equation is subject to either two-point boundary conditions or initial conditions.
Atanackovic, T.M, Djukic, Dj.S
core   +1 more source

Estimating the variance in coordinate measuring for binary orbit

open access: yesJournal of Geodetic Science, 2015
The variance of a purely random error - “pure error” - in measuring the relative coordinates during the calculation of the orbits of binary stars, (its "unbiased estimate"), is necessary for each test used in the orbit calculation for double stars, such ...
Perović G., Cvetković Z.
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

A generalization error estimate for nonlinear systems [PDF]

open access: yes, 1992
A new estimate (GEN) of the generalization error is presented. The estimator is valid for both incomplete and nonlinear models. An incomplete model is characterized in that it does not model the actual nonlinear relationship perfectly.
J. Larsen, Larsen, Jan
core   +1 more source

Time discretization of an abstract problem from linearized equations of a coupled sound and heat flow

open access: yesElectronic Journal of Differential Equations, 2020
Recently, a time discretization of simultaneous abstract evolution equations applied to parabolic-hyperbolic phase-field systems has been studied. This article focuses on a time discretization of an abstract problem that has application to linearized
Shunsuke Kurima
doaj  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Error report for: Hehman et al. (2018).

open access: yes
DECISION AND RECOMMENDATION Hehman et al. (2018) “Disproportionate Use of Lethal Force in Policing Is Associated With Regional Racial Biases” was determined to contain a Major Error that affects a core conclusion.
ERROR
core   +1 more source

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