Results 61 to 70 of about 856,472 (265)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Spectral collocation method for convection-diffusion equation

Demonstratio Mathematica
Spectral collocation method, named linear barycentric rational interpolation collocation method (LBRICM), for convection-diffusion (C-D) equation with constant coefficient is considered.
Li Jin, Cheng Yongling
doaj   +1 more source

The Mollification Regularization Method with Truncated Kernels for Solving the Inverse Time-Fractional Schrödinger Problem

Fractal and Fractional
This paper studies an inverse problem associated with the time-fractional Schrödinger equation in a field-free potential. To address the severe ill-posedness of the problem, a mollification regularization method with truncated kernels is employed to ...
Huilin Xu, Fanli Xu, Duanmei Zhou, Rong Zhang   +3 more
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Estimation for the Multivariate Errors-in-Variables Model with Estimated Error Covariance Matrix

The Annals of Statistics, 1984
The authors consider the estimation problem of multivariate errors-in- variables models. Let \(r\times 1\) row vectors \(y_ i\) and \(k\times 1\) row vectors \(x_ i\) satisfy \(y_ i=\beta_ 0+x_ i\beta\), \(i=1,2,...,n\), where \(\beta_ 0\) and \(\beta\) are 1\(\times r\) and \(k\times r\) matrices of parameters, respectively.
Amemiya, Yasuo, Fuller, Wayne A.
openaire   +3 more sources

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Error estimation for quadrature formulas based on equally spaced nodes

Mathematical Modelling and Analysis, 2006
The error estimation for quadrature formulas based on equally spaced nodes is discussed in this paper. The error estimates use embedded formulas and they are obtained for Newton‐Cotes and Hermitian quadrature formulas.
K. Plukas, D. Plukiene
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Superconvergence of Mixed Finite Element Method with Bernstein Polynomials for Stokes Problem

Axioms
In this paper, we employ interpolation and projection methodologies to establish a superconvergence outcome for the Stokes problem, as approximated by the mixed finite element method (FEM) utilizing Bernstein polynomial basis functions.
Lanyin Sun, Siya Wen, Ziwei Dong
doaj   +1 more source