Results 71 to 80 of about 862,081 (264)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Estimation for the Multivariate Errors-in-Variables Model with Estimated Error Covariance Matrix

The Annals of Statistics, 1984
The authors consider the estimation problem of multivariate errors-in- variables models. Let \(r\times 1\) row vectors \(y_ i\) and \(k\times 1\) row vectors \(x_ i\) satisfy \(y_ i=\beta_ 0+x_ i\beta\), \(i=1,2,...,n\), where \(\beta_ 0\) and \(\beta\) are 1\(\times r\) and \(k\times r\) matrices of parameters, respectively.
Amemiya, Yasuo, Fuller, Wayne A.
openaire   +3 more sources

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

A natural boundary element method for the Sobolev equation in the 2D unbounded domain

Boundary Value Problems, 2017
In this article, we devote ourselves to establishing a natural boundary element (NBE) method for the Sobolev equation in the 2D unbounded domain. To this end, we first constitute the time semi-discretized super-convergence format for the Sobolev equation
Fei Teng, Zhendong Luo, Jing Yang
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Finite Element Approximation of Variational Inequalities: An Algorithmic Approach

Sultan Qaboos University Journal for Science, 2018
In this paper, we introduce a new method to analyze the convergence of the standard finite element method for elliptic variational inequalities with noncoercive operators (VI).
Messaoud Boulbrachene
doaj   +1 more source

ERROR ESTIMATION AND ADAPTIVITY IN ELASTOPLASTICITY

International Journal for Numerical Methods in Engineering, 1996
Summary: A method is developed to control the parameters of a finite element computation for time-dependent material models. To evaluate discretization errors, we use a global error measure in constitutive relation based on Drucker's inequality. This error includes, over the studied time interval, the error of the finite element model and the error of ...
Gallimard, L., Ladevèze, Pierre, Pelle, Jean-Pierre   +2 more
openaire   +3 more sources