Results 131 to 140 of about 701,176 (312)

Fourth-Order Compact Finite Difference Method for the Schrödinger Equation with Anti-Cubic Nonlinearity

Mathematics
In this paper, we present a compact finite difference method for solving the cubic–quintic Schrödinger equation with an additional anti-cubic nonlinearity.
He Yang
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Error control in finite element computations An introduction to error estimation and mesh-size adaptation

, 1998
We present a general paradigm for a posteriori error control and adaptive mesh design in finite element Galerkin methods. The conventional strategy for controlling the error in finite element methods is based on a posteriori estimates for the error in ...
Heidelberg Univ. (Germany). Sonderforschungsbereich 359 - Reaktive Stroemungen, Diffusion und Transport, Heidelberg Univ. (Germany). Interdisziplinaeres Zentrum fuer Wissenschaftliches Rechnen (IWR), Rannacher, R. (Heidelberg Univ. (Germany). Inst. fuer Angewandte Mathematik)   +2 more
core  

East Cascades Error Adjusted Area Estimates

, 2017
<p>The files in this folder include the error-adjusted area estimates of seven structural classes for five strata, as well as the annual area burned for each class at different levels of fire severity.
Matthew Reilly (3631417), Matthew Reilly
core   +1 more source

Novel Numerical Investigation of Reaction Diffusion Equation Arising in Oil Price Modeling

Mathematics
Consideration is given to a reaction–diffusion free boundary value problem with one or two turning points arising in oil price modeling. First, an exact (analytical) solution to the reduced problem (i.e., no diffusion term) was obtained for some given ...
Fehaid Salem Alshammari
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Modelling the spatial distribution of DEM Error

, 2005
Assessment of a DEM’s quality is usually undertaken by deriving a measure of DEM accuracy – how close the DEM’s elevation values are to the true elevation.
Carlisle, Bruce
core   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Performance of a new stabilized structure-preserving finite element method for the Allen–Cahn equation

Mathematical and Computer Modelling of Dynamical Systems
This paper presents an energy stable scheme for the numerical solution of the Allen–Cahn equation. The scheme combines the Crank–Nicolson/Adams–Bashforth technique with the Galerkin method, complementing a thoughtfully designed stabilization term.
Panason Manorot, Ben Wongsaijai, Kanyuta Poochinapan   +2 more
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source