Results 111 to 120 of about 701,176 (312)
EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot +36 morewiley +1 more sourceSome recent advances in measurement error models and methods [PDF]
, 2005 Measurement errors, error in variables, misclassification, efficiency comparison, survival analysis. JEL C13, C20, C24, C25,Augustin, Thomas, Thomas Augustin, Hans Schneeweiss, Schneeweiß, Hans +3 morecore +1 more sourceEngineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang +12 morewiley +1 more sourceTowards regional, error-bounded landscape carbon storage estimates for data-deficient areas of the world [PDF]
, 2012 Monitoring landscape carbon storage is critical for supporting and validating climate change mitigation policies. These may be aimed at reducing deforestation and degradation, or increasing terrestrial carbon storage at local, regional and global levels. Burgess, Neil David, Bayliss Julian, Swetnam, R D, Jon C. Lovett (136269), Bayliss, Julian, Ahrends Antje, Lovett, Jon C, Burgess, N D, Owen, Nisha, Munishi, P K T, Fanning Eibleis, Nisha Owen, Ahrends, A, Andrew R Marshall, Pantaleon K T Munishi, Willcock, S, Green, Jonathan, Howell, Kim L., Mbilinyi, Boniface, Julian Bayliss, Lewis, Simon L., Rob Marchant, Elmer J. Topp-Jorgensen (136295), Hall, Jaclyn, Mbiliny, B., Andrew Balmford (104996), Hall Jaclyn, Ahrends, Antje, Boniface Mbilinyi (136287), Lewis, Simon L, Ruth D Swetnam, Julian Bayliss (136089), Lovett, Jon C., Hall, J, Doody, K, Neil D. Burgess (136266), Rob Marchant (136283), Philip J Platts, Marchant, Rob, Swetnam Ruth D., Nike Doggart (136272), Simon Willcock, Nike Doggart, Phillips, O L, Oliver L. Phillips (136260), Topp-Jorgensen, E.J., Doggart, Nike, Phillips, O.L., Platts, P J, Fanning, Eibleis, Doody Kathryn, Howell, K.L., Marchant, R., Topp-Jorgensen, Elmer J, Lewis Simon L., Burgess, ND, Mbilinyi, B, Phillips, Oliver L, Jaclyn Hall, Platts Philip J., Doggart, N.H., Green Jonathan, Minishi, P.K.T., Platts, Philip J, Simon L. Lewis (136299), Topp-Jorgensen, EJ, Kim L Howell, Green, J., Marshall, Andrew R, Green, Jonathan Michael Halsey, Pantaleon K. T. Munishi (136289), Ruth D. Swetnam (136292), Marchant Rob, Lovett, J C, Bayliss, J, Topp-Jorgensen, Elmer J., Green, J, Marshall, A.R., Marchant, R, Antje Ahrends, Jonathan Green, Lewis, S.L., Swetnam, R.D., Munishi, Pantaleon K T, Burgess, Neil D., Doody, Kathryn, Nisha Owen (136290), Phillips, OL, Hall, J., Owen Nisha, Bayliss, J., Mbilinyi Boniface, Antje Ahrends (128927), Willcock, S., Eibleis Fanning, Balmford Andrew, Simon Willcock (136256), Platts, PJ, Topp-Jorgensen Elmer J., Balmford, A, Swetnam, Ruth D., Phillips, Oliver L., Eibleis Fanning (136277), Lewis, SL, Ahrends, A., Willcock Simon, Burgess, N.D., Jaclyn Hall (136279), Kathryn Doody, Munishi, Pantaleon K. T., Owen, N., Lovett, JC, Phillips Oliver L., Howell Kim L., Munishi, Pantaleon K.T., Balmford, Andrew, Jonathan Green (22815), Marshall, AR, Platts, P.J., Kim L. Howell (136281), Lovett Jon C., Doggart, N, Lovett, Jonathan Cranidge, Andrew R. Marshall (136285), Neil D Burgess, Fanning, E., Elmer J Topp-Jorgensen, Philip J. Platts (136263), Willcock, Simon, Fanning, E, Howell, K L, Owen, N, Burgess Neil D., Platts, Philip J., Oliver L Phillips, Howell, Kim, Marshall, Andrew R., Marshall Andrew R., Balmford, A., Burgess, Neil D, Howell, KL, Kathryn Doody (136274), Munishi Pantaleon K. T., Andrew Balmford, Swetnam, RD, Doody, K., Munishi, PKT, Simon L Lewis, Boniface Mbilinyi, Doggart Nike, Jon C Lovett +150 morecore +1 more sourceRegularization and error estimates for nonhomogeneous backward heat problems
Electronic Journal of Differential Equations, 2006 In this article, we study the inverse time problem for the non-homogeneous heat equation which is a severely ill-posed problem. We regularize this problem using the quasi-reversibility method and then obtain error estimates on the approximate ...Duc Trong Dang, Huy Tuan Nguyendoaj IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd +9 morewiley +1 more source
