Results 51 to 60 of about 2,420,035 (290)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

THE SAMPLING ERROR OF ROTATOR ESTIMATES OF EYE VOLUME

open access: yesImage Analysis and Stereology, 2011
The vertical rotator is a design based stereological method for estimating object volume using measurements made on co-axial sections. Recently we used the method to estimate eye volume in a number of pathological studies. In the present note we apply an
Matthew G Reed, CV Howard
doaj   +1 more source

FUNCTIONAL-TYPE A POSTERIORI ERROR ESTIMATES FOR SOLUTIONS IN DEFORMABLE SOLID MECHANICS

open access: yesSt. Petersburg Polytechnical University Journal: Physics and Mathematics, 2020
Paper provides a historical review and recent developments on theoretical justification and numerical implementations of functional a posteriori error estimates and adaptive algorithms for approximate solutions to problems in deformable solid mechanics ...
Valdman Jan, Frolov Maxim
doaj   +1 more source

A Probabilistic Approach for Solutions of Deterministic PDE’s as Well as Their Finite Element Approximations

open access: yesAxioms, 2021
A probabilistic approach is developed for the exact solution u to a deterministic partial differential equation as well as for its associated approximation uh(k) performed by Pk Lagrange finite element.
Joël Chaskalovic
doaj   +1 more source

High-dimensional bolstered error estimation [PDF]

open access: yesBioinformatics, 2011
Abstract Motivation: In small-sample settings, bolstered error estimation has been shown to perform better than cross-validation and competitively with bootstrap with regard to various criteria. The key issue for bolstering performance is the variance setting for the bolstering kernel.
Chao, Sima   +2 more
openaire   +2 more sources

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

On the aposteriori error estimates for finite‐element solutions

open access: yesMathematical Modelling and Analysis, 1998
The analysis of the accuracy of the aposteriori error estimation procedure for finite‐element solutions is presented. The function Y — y is used as an aposteriori error estimator, here y ∈ S 0 1,Δ is the finite‐element solution of the given problem and Y
Raimondas Èiegis
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Recursive POD expansion for the advection-diffusion-reaction equation [PDF]

open access: yes, 2018
This paper deals with the approximation of advection-diffusion-reaction equation solution by reduced order methods. We use the Recursive POD approximation for multivariate functions introduced in [M. AZAÏEZ, F. BEN BELGACEM, T. CHACÓN REBOLLO, Recursive
Azaïez, Majdi   +3 more
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

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