Results 81 to 90 of about 9,541,376 (284)

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Numerical simulation of wind field error of ultrasonic wind speed sensor

Meikuang Anquan
In order to study the influence of the wind field error on the measurement results of the mine ultrasonic time difference wind speed sensor, the computational fluid dynamics method was used to analyze the flow field and acoustic channel velocity ...
Renyong GU, Ze JIANG, Lu WANG, Yejun HAO
doaj   +1 more source

Error report for: Hehman et al. (2018).

DECISION AND RECOMMENDATION Hehman et al. (2018) “Disproportionate Use of Lethal Force in Policing Is Associated With Regional Racial Biases” was determined to contain a Major Error that affects a core conclusion.
ERROR
core   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Simulating Error Due to Acquired Thermoelectric Inhomogeneity

Sensors
The best method to prevent error due to inhomogeneity is to use a new thermocouple design—the thermocouple with controlled temperature field (TCTF). It uses the auxiliary furnace to control the temperature field along its legs.
Zida Li, Jingliang Chen
doaj   +1 more source

PIV Based Pressure Field Measurement Technique for Open-channel Turbulence

工程科学与技术, 2023
PIV-based pressure field measurement technique enables a non-intrusive, high spatial and temporal resolution and full-field measurement of the instantaneous pressure of flows.
Zhongxiang WANG, Qigang CHEN, Yanchong DUAN, Qiang ZHONG   +3 more
doaj  

Error report for Lades et al. (2020)

DECISION AND RECOMMENDATION Lades, Laffan, Daly, & Delaney (2020) “Daily emotional well‐being during the COVID‐19 pandemic” was determined to contains Moderate Errors that do not affect the core conclusions.
ERROR
core   +1 more source

Error Algebras [PDF]

, 2007
In computations over many-sorted algebras, one typically encounters error cases, caused by attempting to evaluate an operation outside its domain (e.g.
Lei, Wei
core  

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source