Systemic immune dysregulation in patients experiencing urogynaecological mesh failure. [PDF]
Jamieson S +9 more
europepmc +1 more source
ABSTRACT Class Switch Recombination (CSR) is essential for generating high‐affinity antibody isotypes from IgM during adaptive humoral responses. Despite well‐established roles for various transcription factors, whether CSR is subject to dedicated post‐transcriptional control represents a significant gap in knowledge.
Siyuan Sun +19 more
wiley +1 more source
Measurement properties of the Sexual Risk Behaviors Scale (SRBS) in university students in Brazil. [PDF]
Dalmolin J +6 more
europepmc +1 more source
We investigate the geometry‐governed optoelectronic anisotropy arising from dielectric confinement in quasi‐1D γ‐GaS nanoribbons with intrinsically isotropic atomic structures. Dielectric mismatch between the nanoribbon and its surroundings leads to a general polarization‐dependent photoresponse during near‐field scattering.
Jiawei Jing +16 more
wiley +1 more source
Assessing upper limb function: the Spanish version of the Stroke Upper Limb Capacity Scale (SULCS): cross-cultural adaptation and clinimetric properties. [PDF]
Gómez-Ortega A +4 more
europepmc +1 more source
A unique mechanism of catalytic bias regulated by diaphorase‐like subunit in formate dehydrogenase from Rhodobacter aestuarii is revealed. The diaphorase‐like subunit functions act as a biological “voltage rheostat” that controls the slow release of NADH to regulate redox balance, biasing the enzyme's catalytic preference toward CO2 reduction over ...
Kuncheng Zhang +7 more
wiley +1 more source
Automated extraction of the plane of minimal hiatal dimensions and mid-sagittal plane from 3D transperineal ultrasound. [PDF]
Szentimrey Z +5 more
europepmc +1 more source
PlantGFM: A Genomic Foundation Model for Discovery and Creation of Plant Genes
A plant genomic foundation model pre‐trained on 12 species enables both accurate gene prediction and de novo gene design. Through AI‐human knowledge screening, seven designed sequences showed transcriptional activity in plants, with two expressing stable proteins—demonstrating the first DNA‐RNA‐protein expression of LLM‐generated genes in plants and ...
Changhao Li +10 more
wiley +1 more source
Cone-Beam CT Assessment of the Canalis Sinuosus in an Indian Population: A Retrospective Imaging Study. [PDF]
Denny C +5 more
europepmc +1 more source
Xenogeneic Mitochondrial Transplantation Improves Selected Age‐Associated Phenotypes in Mice
Yak‐derived xenogeneic mitochondrial transplantation improves selected age‐associated phenotypes in mice, enhances mitochondrial functional readouts, and engages host mitochondrial quality‐control pathways. Broad tissue biodistribution, increased ATP production and mtDNA copy number, reduced ROS levels and dysfunctional mitochondria, improved motility ...
Wenpeng Li +5 more
wiley +1 more source

