Results 91 to 100 of about 2,660,340 (290)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Study on Error Pattern of Consonant of Children with Functional Dysarthria

open access: yes康复学报, 2015
Objective:To study the distribution characteristics, error pattern and acquistion features of disordered consonants of children with functional dysarthria, so as to provide the theoretical guidance for the design of pronunciation rehabilitation programs ...
Zhihong DU   +4 more
doaj  

Error Models of the Analog to Digital Converters

open access: yesMeasurement Science Review, 2014
Error models of the Analog to Digital Converters describe metrological properties of the signal conversion from analog to digital domain in a concise form using few dominant error parameters.
Michaeli Linus, Šaliga Ján
doaj   +1 more source

An Overview of Robotics in Functional Neurosurgery

open access: yesIndian Journal of Neurosurgery, 2019
Stereotactic techniques are used in a wide range of neurosurgical procedures. The procedures demand a high degree of spatial accuracy and minimal error.
Vikas Vazhayil   +5 more
doaj   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Black box systems identification with estimation

open access: yesRevista Facultad de Ingeniería Universidad de Antioquia, 2014
In  a  black  box  system  the  internal  parameters  are  not  observables  between  input-output relationships. An approach is made knowing as estimation, based on the second probability moment. These results with a functional error and the innovation
María Teresa Zagceta Álvarez   +2 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Uncertainty Quantification of Complex Weather Dynamics Using a Novel Functional Autoregressive Model

open access: yesMathematics
Functional time series (FTS) modeling has emerged as a powerful framework for capturing complex temporal dependencies using the functional autoregressive models FAR(p, m) and FARX(p, m, τ). These functional models characterize the evolution of functional
Ismail Shah   +3 more
doaj   +1 more source

Consistency of the recursive nonparametric regression estimation for dependent functional data

open access: yes, 2013
We consider the recursive estimation of a regression functional where the explanatory variables take values in some functional space. We prove the almost sure convergence of such estimates for dependent functional data.
Amiri, Aboubacar, Thiam, Baba
core   +1 more source

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