Results 61 to 70 of about 649,705 (315)
Estimation error probability projection-based stereology.
A. Estimation error is distributed according to the shown probability densities (axon classes in columns; red, green, and blue for XY, XZ, and YZ planes respectively). The probability of getting a certain error during axon length estimation will be given
Sergio Díez-Hermano (11813174) +7 more
core +1 more source
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Background. To substantiate the reliability assessment of the operating personnel at a nuclear power plant (NPP) under conditions of increasing load, it is necessary to specify the existing general patterns of the functional state dynamics depending on ...
Elena D. Chernetskaya +3 more
doaj +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Error Probabilities for Halfspace Depth
Data depth functions are a generalization of one-dimensional order statistics and medians to real spaces of dimension greater than one; in particular, a data depth function quantifies the centrality of a point with respect to a data set or a probability distribution. One of the most commonly studied data depth functions is halfspace depth.
Michael A. Burr, Robert Fabrizio
openaire +2 more sources
On the Symbol Error Probability of Regular Polytopes [PDF]
An exact expression for the symbol error probability of the four-dimensional 24-cell in Gaussian noise is derived. Corresponding expressions for other regular convex polytopes are summarized. Numerically stable versions of these error probabilities are also obtained.
Erik Agrell, Magnus Karlsson 0001
openaire +2 more sources
Consistent estimation in an implicit quadratic measurement error model
An adjusted least squares estimator is derived that yields a consistent estimate of the parameters of an implicit quadratic measurement error model. In addition, a consistent estimator for the measurement error noise variance is proposed.
Er Kukush +5 more
core +1 more source
An error bound analysis for M-DPSK in frequency-selective Rayleigh fading channel with diversity reception [PDF]
A theoretical upper bound is presented to calculate the error probability for raised cosine filtered M-ary differential phase-shift keying (RC M-DPSK) in frequency-selective Rayleigh fading channels.
Nix, AR, Chow, YC, McGeehan, JP
core +1 more source
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source

