Results 161 to 170 of about 18,518,960 (329)

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Shift Volume Directly Impacts Neuroradiology Error Rate at a Large Academic Medical Center: The Case for Volume Limits. [PDF]

AJNR Am J Neuroradiol
Ivanovic V, Broadhead K, Chang YM, Hamer JF, Beck R, Hacein-Bey L, Qi L.   +6 more
europepmc   +2 more sources

Forensic science and the principle of excluded middle: "Inconclusive" decisions and the structure of error rate studies. [PDF]

Forensic Sci Int Synerg, 2021
Biedermann A, Kotsoglou KN.
europepmc   +1 more source

Modeling the effect of technology trends on the soft error rate of combinational logic

Proceedings : International Conference on Dependable Systems and Networks, 2002
Premkishore Shivakumar, M. Kistler, S. Keckler, D. Burger, L. Alvisi   +4 more
semanticscholar   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Design and Analysis of Soft Error Rate in FET/CNTFET Based Radiation Hardened SRAM Cell. [PDF]

Sensors (Basel), 2021
Muthu BR, Pushpa EP, Dhandapani V, Jayaraman K, Vasanthakumar H, Oh WC, Sagadevan S.   +6 more
europepmc   +1 more source

Do p Values Lose Their Meaning in Exploratory Analyses? It Depends How You Define the Familywise Error Rate

, 2017
Mark Rubin
semanticscholar   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Comparison of ONT and CCS sequencing technologies on the polyploid genome of a medicinal plant showed that high error rate of ONT reads are not suitable for self-correction. [PDF]

Chin Med, 2022
Zeng P, Tian Z, Han Y, Zhang W, Zhou T, Peng Y, Hu H, Cai J.   +7 more
europepmc   +1 more source