Results 41 to 50 of about 107,750 (302)

Error-Trellis Construction for Convolutional Codes Using Shifted Error/Syndrome-Subsequences

IEICE Transactions on Fundamentals of Electronics, Communications and Computer Sciences, 2009
In this paper, we extend the conventional error-trellis construction for convolutional codes to the case where a given check matrix H(D) has a factor Dl in some column (row). In the first case, there is a possibility that the size of the state space can be reduced using shifted error-subsequences, whereas in the second case, the size of the state space
TAJIMA, Masato, OKINO, Koji, MIYAGOSHI, Takashi   +2 more
openaire   +1 more source

Analysis of Absorbing Sets using Cosets and Syndromes

, 2020
Absorbing sets are combinatorial structures in a Tanner graph that have been shown to characterize iterative decoder failure, and particularly error floor behavior, of LDPC codes.
Emily McMillon, McMillon, Emily, Kelley, Christine A., Allison Beemer, Beemer, Allison, Christine A. Kelley   +5 more
core   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

A TWO-STAGE APPROACH FOR COMBINING GENE EXPRESSION AND MUTATION WITH CLINICAL DATA IMPROVES SURVIVAL PREDICTION IN MYELODYSPLASTIC SYNDROMES AND OVARIAN CANCER

Journal of Bioinformatics and Genomics, 2016
Motivation: Many traditional clinical prognostic factors have been known for cancer for years, but usually provide poor survival prediction. Genomic information is more easily available now which offers opportunities to build more accurate prognostic ...
Yan Li, Xinyan Zhang, Tomi Akinyemiju, Akinyemi I. Ojesina, Jeff M. Szychowski, Nianjun Liu, Bo Xu, Nengjun Yi   +7 more
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

An Iterative Error Patterns Library Formation Method for the Decoding of Product Codes [PDF]

, 2021
Product codes are preferred in high data rate wireless communication systems to achieve good error performance. In this paper, the problem of twodimensional syndrome-norm decoding of product codes based on a library of error patterns is considered.
Tsviatkou, V. Y., Конопелько, В. К., Konopelko, V., Jun Ma, Xunhuan Ren, Цветков, В. Ю.   +5 more
core  

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

The Role of the Dorsolateral Prefrontal Cortex for Speech and Language Processing

Frontiers in Human Neuroscience, 2021
This review article summarizes various functions of the dorsolateral prefrontal cortex (DLPFC) that are related to language processing. To this end, its connectivity with the left-dominant perisylvian language network was considered, as well as its ...
Ingo Hertrich, Susanne Dietrich, Corinna Blum, Hermann Ackermann   +3 more
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Estudo epidemiológico de cardiopatias congênitas nas maternidade Carmela Dutra: Período de 01 de setembro de 1992 a 31 de dezembro de 1998. [PDF]

, 1999
Trabalho de Conclusão de Curso - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Departamento de Pediatria, Curso de Medicina, Florianópolis ...
Bernardi, Pricila
core