Results 71 to 80 of about 208,269 (282)

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Evolutionary fuzzy learning for Chinese medicine liver syndrome differentiation

Systems Science & Control Engineering
As a basic principle in traditional Chinese medicine (TCM), syndrome differentiation is a comprehensive analysis of clinical information to provide evidence for treatment, which is a task that heavily relies on the subjective experience of TCM doctors ...
Jia-Yu Yan, Peng-Wei Zhang, Wei-Guo Sheng, Jun-Ping Shi, Wei Ni, Li Li, Yu-Jun Zheng   +6 more
doaj   +1 more source

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

Experimentally informed decoding of stabilizer codes based on syndrome correlations

Physical Review Research
High-fidelity decoding of quantum error correction codes relies on an accurate experimental model of the physical errors occurring in the device. Because error probabilities can depend on the context of the applied operations, the error model is ideally ...
Ants Remm, Nathan Lacroix, Lukas Bödeker, Elie Genois, Christoph Hellings, François Swiadek, Graham J. Norris, Christopher Eichler, Alexandre Blais, Markus Müller, Sebastian Krinner, Andreas Wallraff   +11 more
doaj   +1 more source

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon, Nathalie Picard, Valeria d'Andrea, Enchi Chang, Joseph Leffler, Eleonora Centofante, Matthew Taylor, Francesca Bardi, Francesca Cavicchiolo, Takao K. Hensch, Stefano Panzeri, Chinfei Chen, Michela Fagiolini   +12 more
wiley   +1 more source

Codes on s-periodic errors

Ratio Mathematica, 2012
In this paper, we study linear codes capable of detecting and correcting s-periodic errors. Lower and upper bounds on the number of parity check digits required for codes detecting such errors are obtained.
Pankaj Kumar Das, Vinod Tyagi
doaj  

Electroencephalography: electrode arrays in dogs

Frontiers in Veterinary Science
Electroencephalography (EEG) is the gold standard for confirming epileptic seizures in both human and veterinary patients. Despite idiopathic epilepsy being one of the most common neurological conditions in dogs, our understanding of it in veterinary ...
Stephen Everest, Luis Gaitero, Robert Dony, Alexander Zur Linden, Miguel A. Cortez, Fiona M. K. James   +5 more
doaj   +1 more source

A patient-centered deprescribing intervention for hospitalized older patients with polypharmacy: rationale and design of the Shed-MEDS randomized controlled trial

BMC Health Services Research, 2019
Background Polypharmacy is prevalent among hospitalized older adults, particularly those being discharged to a post-care care facility (PAC). The aim of this randomized controlled trial is to determine if a patient-centered deprescribing intervention ...
Eduard E. Vasilevskis, Avantika S. Shah, Emily K. Hollingsworth, Matthew S. Shotwell, Amanda S. Mixon, Susan P. Bell, Sunil Kripalani, John F. Schnelle, Sandra F. Simmons, the Shed-MEDS Team   +9 more
doaj   +1 more source

The Impact of Tilburg Frailty on Poststroke Fatigue in First‐Ever Stroke Patients: A Cross‐Sectional Study With Unified Measurement Tools and Improved Statistics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Poststroke fatigue (PSF) and frailty share substantial overlap in their manifestations, yet previous research has yielded conflicting results due to the use of heterogeneous frailty assessment tools. Objective To evaluate the independent impact of frailty on PSF using a unified measurement system (Tilburg Frailty Indicator, TFI ...
Chuan‐Bang Chen, Xiao‐Xue Wang, Shao‐Rui Bao, Sui‐Li Lin, Mei‐Chun Shu, Xi‐Xi Ye, Wen‐Jie Cong   +6 more
wiley   +1 more source

Prediction Model for Etiologic Differentiation of Isolated Vestibular Syndrome in Emergency Settings

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to develop and validate a predictive model for differentiating central from peripheral etiologies in patients with isolated vestibular syndrome (VS). Methods In this multicenter retrospective cohort study, 506 patients with isolated VS from five hospitals were divided into derivation (n = 301) and validation (n = 205)
Guo Wenting, Du Liping, Yang Yi, Hu Jin, Ye Bijun, Wang Jianer, Liu Shuangsi, Guo Shunyuan, Cai Xiaofeng, Wang Huiyuan, Wu Bin, Yu Xiang, Shi Tianming   +12 more
wiley   +1 more source