Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Disposition characteristics of pathopsychological register−syndromes, psychopathological syndromes and clinical psychotherapeutic effect−syndromes [PDF]
Приведены результаты исследования диспозиционной иерархии патопсихологической регистр−синдромологии, психопатологической синдромологии и клинической психотерапевтической синдромологии.
Чугунов, В. В.
core +1 more source
Some of childhood epileptic syndromes reminds immunological etiologies with their good response to immuno-therapy and histopathological findings. These syndromes, such as Rasmussen encephalitis, FIRES, West syndrome, and Landau-Kleffner syndrome each of ...
Demet KINAY, Pınar TEKTÜRK
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Hypereosinophilic Syndromes [PDF]
In den vergangenen Jahren wurden zahlreiche neue Erkenntnisse zur Biologie eosinophiler Granulozyten, ihrer Rolle für die Gesundheit und bei Krankheiten gewonnen.
Houriet, C., Simon, H.-U., Simon, D.
core +2 more sources
Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi +8 more
wiley +1 more source
Analysis of syndrome decoding methods for Reed–Solomon codes
Methods of syndrome decoding are considered. The possibility of various approaches to decoding Reed–Solomon codes is shown. It is concluded that the development of non-recursive decoding procedures is necessary, which can be achieved through the use of ...
I. V. Ivanova
doaj
PROPERTIES OF GROUPS G OF DOUBLE ERRORS AND ITS INVARIANTS IN BCH CODES
The goal of the work is the further extending the scope of application of code automorthism in methods and algorithms of error correction by these codes. The effectiveness of such approach was demonstrated by norm of syndrome theory that was developed by
V. A. Lipnitskij, A. V. Serada
doaj +1 more source
Megalencephaly syndromes: exome pipeline strategies for detecting low-level mosaic mutations [PDF]
Two megalencephaly (MEG) syndromes, megalencephaly-capillary malformation (MCAP) and megalencephaly-polymicrogyriapolydactyly?-hydrocephalus(MPPH), have recently been defined on the basis of physical and neuroimaging features.
Cross, Nicholas C. P. +32 more
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RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu +21 more
wiley +1 more source
Fully Automatic Landmarking of Syndromic 3D Facial Surface Scans Using 2D Images
3D facial landmarks are known to be diagnostically relevant biometrics for many genetic syndromes. The objective of this study was to extend a state-of-the-art image-based 2D facial landmarking algorithm for the challenging task of 3D landmark ...
Jordan J. Bannister +9 more
doaj +1 more source

