Results 61 to 70 of about 72,397 (309)
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Sistema de reconocimiento de voz: un enlace en la comunicación hombre-máquina
Un sistema de reconocimiento de voz es la capacidad que presenta un ordenador para recibir los datos de voz de un usuario, transformar la señal en código binario, el cual es asimilado por la computadora y luego establece la comunicación hombremáquina ...
Kiara Barrios +4 more
doaj +1 more source
Error and Error Reduction in Pathology
Abstract Context.—Since publication of the Institute of Medicine's report on medical error in late 1999, there has been widespread interest in improving patient safety and in error reduction in all disciplines of medicine. In fields other than medicine, considerable knowledge has been obtained concerning error and error reduction ...
openaire +2 more sources
The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
4. Errores y tratamiento de errores orales en el salón de lengua extranjera: una revisión
Existe controversia sobre la percepción de los errores como parte del proceso de aprendizaje de una lengua y en la literatura se observa un amplio rango de términos relacionados con el tratamiento de errores.
Bexi Perdomo
doaj +1 more source
The Error of Counting “Errors”
I don’t understand why people are frightened of new ideas; I’m frightened of old ones. —John Cage There are 2 fundamentally opposed ways to look at “human errors”; we can see “error” as a cause of failures, or we can see “error” as a consequence, a symptom of problems deeper in the organization.
Department of Emergency Medicine, University of Florida, Jacksonville, FL, and Clinical Safety Research Unit, Imperial College, London, UK ( host institution ) +1 more
openaire +2 more sources
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
La presente investigación persigue el objetivo de determinar los errores gramaticales por interferencia lingüística de la (LM) en la adquisición del inglés como lengua extranjera (LE) en los estudiantes del séptimo semestre de Educación Mención Inglés ...
Pérez Rosales, Ana Gabriela
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