Results 61 to 70 of about 72,397 (309)

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Sistema de reconocimiento de voz: un enlace en la comunicación hombre-máquina

open access: yesRevista de Iniciación Científica, 2018
Un sistema de reconocimiento de voz es la capacidad que presenta un ordenador para recibir los datos de voz de un usuario, transformar la señal en código binario, el cual es asimilado por la computadora y luego establece la comunicación hombremáquina ...
Kiara Barrios   +4 more
doaj   +1 more source

Error and Error Reduction in Pathology

open access: yesArchives of Pathology & Laboratory Medicine, 2005
Abstract Context.—Since publication of the Institute of Medicine's report on medical error in late 1999, there has been widespread interest in improving patient safety and in error reduction in all disciplines of medicine. In fields other than medicine, considerable knowledge has been obtained concerning error and error reduction ...
openaire   +2 more sources

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

4. Errores y tratamiento de errores orales en el salón de lengua extranjera: una revisión

open access: yesEducare, 2015
Existe controversia sobre la percepción de los errores como parte del proceso de aprendizaje de una lengua y en la literatura se observa un amplio rango de términos relacionados con el tratamiento de errores.
Bexi Perdomo
doaj   +1 more source

The Error of Counting “Errors”

open access: yesAnnals of Emergency Medicine, 2008
I don’t understand why people are frightened of new ideas; I’m frightened of old ones. —John Cage There are 2 fundamentally opposed ways to look at “human errors”; we can see “error” as a cause of failures, or we can see “error” as a consequence, a symptom of problems deeper in the organization.
Department of Emergency Medicine, University of Florida, Jacksonville, FL, and Clinical Safety Research Unit, Imperial College, London, UK ( host institution )   +1 more
openaire   +2 more sources

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Descripción de los errores gramaticales por interferencia lingüística de la lengua materna en la adquisición del inglés como lengua extranjera en estudiantes de inglés

open access: yes, 2014
La presente investigación persigue el objetivo de determinar los errores gramaticales por interferencia lingüística de la (LM) en la adquisición del inglés como lengua extranjera (LE) en los estudiantes del séptimo semestre de Educación Mención Inglés ...
Pérez Rosales, Ana Gabriela
core  

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