Results 51 to 60 of about 621,842 (299)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Identifiability of logistic regression with homoscedastic error: Berkson model

open access: yesModern Stochastics: Theory and Applications, 2015
We consider the Berkson model of logistic regression with Gaussian and homoscedastic error in regressor. The measurement error variance can be either known or unknown. We deal with both functional and structural cases.
Sergiy Shklyar
doaj   +1 more source

This Is Not a Myeloproliferative Neoplasm…

open access: yes
Pediatric Blood &Cancer, EarlyView.
Stephanie Juané Kennedy
wiley   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Resolving the Errors-in-Variables Bias in Risk Premium Estimation [PDF]

open access: yes, 2014
The Fama-Macbeth (1973) rolling-B method is widely used for estimating risk premiums, but its inherent errors-in-variables bias remains an unresolved problem, particularly when using individual assets or macroeconomic factors.
Pukthuanthong, Kuntara   +2 more
core   +1 more source

Self-Consistent Density Estimation in the Presence of Errors-in-Variables

open access: yesAbstract and Applied Analysis, 2014
This paper considers the estimation of the common probability density of independent and identically distributed variables observed with additive measurement errors.
Junhua Zhang, Yuping Hu, Sanying Feng
doaj   +1 more source

Using lexical variables to predict picture-naming errors in jargon aphasia

open access: yesFrontiers in Psychology, 2015
Introduction Individuals with jargon aphasia produce fluent output which often comprises high proportions of non-word errors (e.g., maf for dog). Research has been devoted to identifying the underlying mechanisms behind such output.
Catherine Godbold
doaj   +1 more source

CO-REGISTRATION OF 3D POINT CLOUDS BY USING AN ERRORS-IN-VARIABLES MODEL [PDF]

open access: yesThe International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2012
Co-registration of point clouds of partially scanned objects is the first step of the 3D modeling workflow. The aim of co-registration is to merge the overlapping point clouds by estimating the spatial transformation parameters. In the literature, one of
U. Aydar   +3 more
doaj   +1 more source

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