Results 71 to 80 of about 630,158 (264)

Scaled weighted total least-squares adjustment for partial errors-in-variables model

Journal of Geodetic Science, 2016
Scaled total least-squares (STLS) unify LS, Data LS, and TLS with a different choice of scaled parameter. The function of the scaled parameter is to balance the effect of random error of coefficient matrix and observation vector for the estimate of ...
Zhao J.
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Spatial‐statistical downscaling with uncertainty quantification in biodiversity modelling

Methods in Ecology and Evolution
Accurate downscaling with uncertainty quantification and its inclusion in fitting biodiversity models to data are essential for accurate, valid inferences and predictions.
Xiaotian Zheng, Noel Cressie, David A. Clarke, Melodie A. McGeoch, Andrew Zammit‐Mangion   +4 more
doaj   +1 more source

Optimization bias in forest management planning solutions due to errors in forest variables

Silva Fennica, 1999
The yield of various forest variables is predicted by means of a simulation system to provide information for forest management planning. These predictions contain many kinds of uncertainty, for example, prediction and measurement errors.
Kangas, Annika, Kangas, Jyrki
doaj   +1 more source

Non-negative variance component estimation for the partial EIV model by the expectation maximization algorithm

Geomatics, Natural Hazards & Risk, 2020
A difficulty in variance component estimation (VCE) is that the estimates may become negative, which is not acceptable in practice. This article presents two new methods for non-negative VCE that utilize the expectation maximization algorithm for the ...
Leyang Wang, Qiwen Wu
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Errors-in-variables and validation problems in reaction norm predictions for wild populations [PDF]

Modeling, Identification and Control
Studies of phenotypic responses in wild populations are often based on reaction norm models where the environmental drivers in many cases are related to climate change.
Rolf Ergon
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Practical Consequences of the Bias in the Laplace Approximation to Marginal Likelihood for Hierarchical Models

Entropy
Due to the high dimensional integration over latent variables, computing marginal likelihood and posterior distributions for the parameters of a general hierarchical model is a difficult task.
Subhash R. Lele, C. George Glen, José Miguel Ponciano   +2 more
doaj   +1 more source