Results 71 to 80 of about 83,889,227 (308)
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Self-Consistent Density Estimation in the Presence of Errors-in-Variables
This paper considers the estimation of the common probability density of independent and identically distributed variables observed with additive measurement errors.
Junhua Zhang, Yuping Hu, Sanying Feng
doaj +1 more source
Using lexical variables to predict picture-naming errors in jargon aphasia
Introduction Individuals with jargon aphasia produce fluent output which often comprises high proportions of non-word errors (e.g., maf for dog). Research has been devoted to identifying the underlying mechanisms behind such output.
Catherine Godbold
doaj +1 more source
CO-REGISTRATION OF 3D POINT CLOUDS BY USING AN ERRORS-IN-VARIABLES MODEL [PDF]
Co-registration of point clouds of partially scanned objects is the first step of the 3D modeling workflow. The aim of co-registration is to merge the overlapping point clouds by estimating the spatial transformation parameters. In the literature, one of
U. Aydar +3 more
doaj +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Nonparametric regression for dependent data in the errors-in-variables problem [PDF]
We consider the nonparametric estimation of the regression functions for dependent data. Suppose that the covariates are observed with additive errors in the data and we employ nonparametric deconvolution kernel techniques to estimate the regression ...
Toshio Honda
core
Prediction of treatments effects in a biased allocation model
Robbins and Zhang [15] provide consistent estimators of multiplicative treatment effects under a biased treatment allocation scheme, and illustrate their methodology within Poisson and binomial models.
Fernando J.M. Magalhães
doaj +1 more source
In this paper, we estimate the mean of the partially linear single-index errors-in-variables model with missing response variables. The linear covariate is measured with additive error, therefore missing is not random.
Xin Qi, ZhuoXi Yu
doaj +1 more source

