Results 81 to 90 of about 115,312,801 (300)
Scaled weighted total least-squares adjustment for partial errors-in-variables model
Scaled total least-squares (STLS) unify LS, Data LS, and TLS with a different choice of scaled parameter. The function of the scaled parameter is to balance the effect of random error of coefficient matrix and observation vector for the estimate of ...
Zhao J.
doaj +1 more source
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Spatial‐statistical downscaling with uncertainty quantification in biodiversity modelling
Accurate downscaling with uncertainty quantification and its inclusion in fitting biodiversity models to data are essential for accurate, valid inferences and predictions.
Xiaotian Zheng +4 more
doaj +1 more source
Optimization bias in forest management planning solutions due to errors in forest variables
The yield of various forest variables is predicted by means of a simulation system to provide information for forest management planning. These predictions contain many kinds of uncertainty, for example, prediction and measurement errors.
Kangas, Annika, Kangas, Jyrki
doaj +1 more source
A difficulty in variance component estimation (VCE) is that the estimates may become negative, which is not acceptable in practice. This article presents two new methods for non-negative VCE that utilize the expectation maximization algorithm for the ...
Leyang Wang, Qiwen Wu
doaj +1 more source
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
A PRIMAL-DUAL ESTIMATOR OF PRODUCTION AND COST FUNCTIONS WITHIN AN ERRORS-IN-VARIABLES CONTEXT [PDF]
In 1944, Marschak and Andrews published a seminal paper on how to obtain consistent estimates of a production technology. The original formulation of the econometric model regarded the joint estimation of the production function together with the first ...
Caputo, Michael R., Paris, Quirino
core
Errors-in-variables and validation problems in reaction norm predictions for wild populations [PDF]
Studies of phenotypic responses in wild populations are often based on reaction norm models where the environmental drivers in many cases are related to climate change.
Rolf Ergon
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source

