Results 61 to 70 of about 2,244,731 (317)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Kesalahan Terjemahan dalam Subtitle Film The Help dan Hidden Figures

open access: yesDiglosia, 2020
The aim of this study was to determine the cultural translation errors in aspect of gender and racial discrimination in movies subtitles The Help and Hidden Figures. This study used a qualitative approach and content analysis method by Krippendorff (2004)
Meliyanti Sihotang   +2 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Social Networks and the Regulatory Function of Language: Internet Debates on Virtual Verbal Intelligence

open access: yesВиртуальная коммуникация и социальные сети, 2023
The article describes the regulatory function of the language of Internet communication. The research featured the Internet discussion triggered by Olga Yurochkina's blog called The Little Things of Life.
Natalya B. Lebedeva
doaj   +1 more source

Meaningful Categorisation of Novice Programmer Errors [PDF]

open access: yes, 2014
The frequency of different kinds of error made by students learning to write computer programs has long been of interest to researchers and educators. In the past, various studies investigated this topic, usually by recording and analysing compiler error
Michael Kolling   +3 more
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Part-time versus full-time occlusion therapy for treatment of amblyopia: A meta-analysis

open access: yesJournal of Current Ophthalmology, 2017
Purpose: To compare full-time occlusion (FTO) and part-time occlusion (PTO) therapy in the treatment of amblyopia, with the secondary aim of evaluating the minimum number of hours of part-time patching required for maximal effect from occlusion. Methods:
Negareh Yazdani   +5 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Evaluation of the CRISPR/Cas9 system as genome editing platform for the Mucopolysaccharidosis IV A using a strategy for induction of higher homologous recombination frequency

open access: yesUniversitas Scientiarum
Mucopolysaccharidosis IVA (MPS IVA) is a lysosomal storage disease caused by mutations in the gene encoding for the hydrolase N-acetylgalactose-6-sulfate sulfatase (GALNS). GALNS deficiency leads to a progressive buildup of partially degraded chondroitin-
Diego Alejandro Suarez   +2 more
doaj   +1 more source

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