Results 81 to 90 of about 2,254,019 (317)
PharmaceuticsBackground/Objectives: Tay–Sachs disease (TSD) is a neurodegenerative disorder caused by a deficiency in β-hexosaminidase A (HexA), which accumulates GM2 gangliosides, primarily in neurons.
Jacky M. Guerrero-Vargas +6 more
doaj +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Clustered standard errors in Stata [PDF]
A brief survey of clustered errors, focusing on estimating cluster–robust standard errors: when and why to use the cluster option (nearly always in panel regressions), and implications.
Austin Nichols, Mark E Schaffer
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Consistent estimation in the bilinear multivariate errors-in-variables model [PDF]
, 2003 A bilinear multivariate errors-in-variables model is considered. It corresponds to an overdetermined set of linear equations AXB=C, A?Rm×n, B?Rp×q, in which the data A, B, C are perturbed by errors.
Van Huffel, S. +2 more
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Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Glottodidactica, 2015 Interlingual transfer is a well known phenomenon. Thanks to many psycholinguistic studies it is now known which factors can induce or hinder this kind of transfer.
Zofia Chłopek
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Identifiability of clock synchronization errors: a behavioural approach [PDF]
, 2009 The subject area of this paper is discrete-time linear time-invariant systems composed of subsystems whose state updating is asynchronous due to the clock signal arriving with delays.
Przedwojski, M, Rogers, E, Markovsky, I
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The complexity of late medication errors [PDF]
, 2022 The medication administration process is complex and frequently leads to errors. Medication errors have a global impact of over $42 billion annually, and in the US an impact of over $21 billion annually. Medication errors have been researched for over 20
Estes, Carey J. +1 more
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