Results 61 to 70 of about 2,293,164 (298)

Estimation of the mean of the partially linear single-index errors-in-variables model with missing response variables

open access: yesJournal of Inequalities and Applications, 2020
In this paper, we estimate the mean of the partially linear single-index errors-in-variables model with missing response variables. The linear covariate is measured with additive error, therefore missing is not random.
Xin Qi, ZhuoXi Yu
doaj   +1 more source

Value and limitations of intracranial recordings for validating electric field modeling for transcranial brain stimulation

open access: yesNeuroImage, 2020
Comparing electric field simulations from individualized head models against in-vivo intra-cranial recordings is considered the gold standard for direct validation of computational field modeling for transcranial brain stimulation and brain mapping ...
Oula Puonti   +3 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Two models for linear comparative calibration [PDF]

open access: yesInternational Journal of Metrology and Quality Engineering, 2012
We consider the comparative calibration problem in the case when linear relationship is assumed between two considered measuring devices with possibly different units and precisions.
Wimmer G., Witkovský V.
doaj   +1 more source

NONPARAMETRIC INSTRUMENTAL REGRESSION WITH ERRORS IN VARIABLES [PDF]

open access: yesEconometric Theory, 2018
This paper considers nonparametric instrumental variable regression when the endogenous variable is contaminated with classical measurement error. Existing methods are inconsistent in the presence of measurement error. We propose a wavelet deconvolution estimator for the structural function that modifies the generalized Fourier coefficients of the ...
Adusumilli, Karun, Otsu, Taisuke
openaire   +3 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Recursive parametrical identification of multidimensional linear dynamic systems with local autocorrelated noises in input and output signals

open access: yesVestnik Samarskogo Gosudarstvennogo Tehničeskogo Universiteta. Seriâ: Fiziko-Matematičeskie Nauki, 2011
The recursive algorithm allowing to receive strongly consistent estimates of parameters of multidimensional on an input linear dynamic systems with locally autocorrelated noise in input and output signals is suggested.
Dmitriy V Ivanov, Oleg A Katsyuba
doaj  

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

On the Interpretation of Instrumental Variables in the Presence of Specification Errors

open access: yesEconometrics, 2015
The method of instrumental variables (IV) and the generalized method of moments (GMM), and their applications to the estimation of errors-in-variables and simultaneous equations models in econometrics, require data on a sufficient number of instrumental ...
P.A.V.B. Swamy   +2 more
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

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