Results 71 to 80 of about 2,080 (215)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Using Latent Variables to Eliminate Multicollinearity Effect in A Logistic Regression on Risk Factors for Breast Cancer

مجله اپیدمیولوژی ایران, 2006
Background and Objectives: Logistic regression is one of the most widely used generalized linear models for analysis of the relationships between one or more explanatory variables and a categorical response.
MA Pourhosseingholi, Y Mehrabi, H Alavi-Majd, P Yavari   +3 more
doaj  

Parameter Estimation Strategies in Thermodynamics

ChemEngineering, 2019
Many thermodynamic models used in practice are at least partially empirical and thus require the determination of certain parameters using experimental data.
Johannes Höller, Patricia Bickert, Patrick Schwartz, Martin von Kurnatowski, Joachim Kerber, Niklaus Künzle, Hilke-Marie Lorenz, Norbert Asprion, Sergej Blagov, Michael Bortz   +9 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Hierarchical Bayesian semi-parametric models for measurement error correction in determining optimal fertilizer application levels

Scientific African
Measurement errors present a substantial challenge in accurately determining optimal fertilizer application levels, directly impacting agricultural efficiency and cost-effectiveness.
Amos Kipkorir Langat, Samuel Musili Mwalili, Lawrence Ndekeleni Kazembe   +2 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Predicting errors in accident hotspots and investigating satiotemporal, weather, and behavioral factors using interpretable machine learning: An analysis of telematics big data.

PLoS ONE
BackgroundRoad traffic accidents (RTAs) are a major public health concern with significant health and economic burdens. Identifying high-risk areas and key contributing factors is essential for developing targeted interventions.
Ali Golestani, Nazila Rezaei, Mohammad-Reza Malekpour, Naser Ahmadi, Seyed Mohammad-Navid Ataei, Sepehr Khosravi, Ayyoob Jafari, Saeid Shahraz, Farshad Farzadfar   +8 more
doaj   +1 more source

The Application of Forecasting Sales of Services to Increase Business Competitiveness

Journal of Competitiveness, 2020
The accurate forecasting of business variables is a key element for a company’s competitiveness which is becoming increasing necessary in this globalized and digitalized environment.
Andrea Kolkova
doaj   +1 more source