Results 41 to 50 of about 21,163 (261)

Effectiveness of geocell wall, geogrid and micropile anchors for mitigation of unstable slopes

Geoenvironmental Disasters, 2021
Slope failure mitigation practices are well developed in recent years. Recently, geosynthetic, geocell, and geogrid combined with micropiles are being used extensively in various slope stabilization works. But integrated approaches are still lacking.
Jain Sanjaya Kumar, Mohammed Saleh Nusari, Dangol Purushotam, Acharya Indra Prasad, Shrestha Rajyaswori   +4 more
doaj   +1 more source

DHODH Drives Sunitinib Resistance Via a Non‐Enzymatic Mechanism by Inhibiting TRIM28 Ubiquitination and Consequent VEGFA Activation in RCC

Advanced Science, EarlyView.
This non‑enzymatic function of DHODH drives sunitinib resistance by competing with TRIM37 to block TRIM28 ubiquitination, thereby stabilizing TRIM28 and activating VEGFA transcription. Disrupting the DHODH–TRIM28 interaction with lisaftoclax restores drug sensitivity.
Shijie Qian, Shihang Pu, Zhipeng Xu, Yiheng Ding, Ling Jin, Baochao Li, Qi Li, Xiaohai Xi, Zengjun Wang, Jiajun Xing, Aiming Xu   +10 more
wiley   +1 more source

Investigating of soil features and landslide risk in Western-Atakent (İstanbul) using resistivity, MASW, Microtremor and boreholes methods

Open Geosciences, 2019
In Western-Atakent (İstanbul), population density is increasing day by day and settlement areas are expanding. Soil properties and landslide conditions of these expanding regions must be absolutely examined. In the geophysics, there are many methods used
Keskinsezer Ayhan, Dağ Ersin
doaj   +1 more source

The Effect of Green Tea as an Adjuvant to Enzyme Replacement Therapy on Oxidative Stress in Fabry Disease: A Pilot Study

Frontiers in Nutrition, 2022
Enzymatic replacement therapy (ERT) is not very effective in halting the progression of Fabry disease (FD) toward cardiovascular (CV)-renal remodeling, particularly in case of late diagnosis. FD patients have increased oxidative stress (OS), critical for
Giovanni Bertoldi, Gianni Carraro, Verdiana Ravarotto, Valentina Di Vico, Paola Baldini Anastasio, Nicola Vitturi, Francesco Francini, Lucia Federica Stefanelli, Lorenzo A. Calò   +8 more
doaj   +1 more source

Non‐Noble Metal Nanocatalysts for Hydrogen Evolution

Advanced Science, EarlyView.
Recent overviews and latest developments of diverse classes of non‐noble catalysts for application toward high‐performance photocatalysis, thermocatalytic steam reforming, and electrocatalysis. Toward sustainability objectives, several advanced characterization tools in combination with the latest breakthroughs in machine learning for material ...
Lina Jaya Diguna, Gede Herry Arum Wijaya, Md Abdul Kuddus Sheikh, Tobias Haposan, Fidelis Stefanus Hubertson Simanjuntak, Arramel Arramel, Muhammad Danang Birowosuto, Konstantin Sergeevich Novoselov   +7 more
wiley   +1 more source

Endovascular Recanalization Therapy in Acute Ischemic Stroke: Updated Meta-analysis of Randomized Controlled Trials [PDF]

Journal of Stroke, 2015
Background and Purpose Recent randomized clinical trials (RCTs) have demonstrated benefits of endovascular recanalization therapy (ERT) contrary to earlier trials.
Keun-Sik Hong, Sang-Bae Ko, Ji Sung Lee, Kyung-Ho Yu, Joung-Ho Rha   +4 more
doaj   +1 more source

Coastal Applications of the ERTS-A Satellite

Coastal Engineering 1972, 1972
This paper describes the Earth Resources Technology Satellite (ERTS) placed in orbit in July 1972 and the ERTS simulation high altitude aircraft flights which have been flown for approximately one year. The ERTS satellite and simulation programs conducted by the National Aeronautics and Space Administration (NASA) have been developed to demonstrate the
Orville T. Magoon, Douglas M. Pirie, John W. Jarman   +2 more
openaire   +2 more sources

RHINO: An Integrative Multi‐Omics Framework Linking Circadian Physiology to Precision Medicine

Advanced Science, EarlyView.
RHINO (RHythmic Interacting Network for multi‐Omics) is an integrative framework that maps circadian regulation across diverse genetic and disease contexts and prioritizes druggable circadian targets. Released as an AI‐powered interactive web portal, RHINO unifies genetic, regulatory, disease, and drug–target information, enabling context‐specific ...
Ying Chen, Chengxuan Chen, Dishu Zhou, Panpan Liu, Roberto E. López‐Valiente, Yuan Liu, Cam Mong La, Isabella Beraldo Xavier, Sean M. Hartig, Pradip Saha, Zheng Sun, Leng Han, Dongyin Guan   +12 more
wiley   +1 more source

Integration of electrical resistivity tomography with electromagnetic and soil radon measurements for characterizing the leakage problem in Afamia B dam, Syria

Geofísica Internacional, 2018
Para comprobar las causas de fuga en la presa Afamia B, y proponer un modelo conceptual, se aplicaron tres técnicas complementarias que incluyen datos tomográficos de resistividad eléctrica (ERT, por sus siglas en inglés), electromagnetismo (EM) y radón ...
Al-Fares Walid, Al-Hilal Mohamed
doaj   +1 more source

Nucleoside‐Modified mRNA Encoding Alpha‐Galactosidase A Ameliorates Fabry Disease Phenotypes in Human IPSC‐Derived Cardiomyocytes

Advanced Science, EarlyView.
Human iPSC‐derived Fabry cardiomyocytes exhibited broad transcriptional dysregulation, apoptosis, mitochondrial dysfunction, impaired reactive oxygen species handling, altered contractility, and abnormal calcium transient decay, potentially mediated by phospholamban hyperphosphorylation.
Malte Juchem, Lea Oehlsen, Sedef Ersoy, Jia Li Ye, Natalie Weber, Elisa Mohr, Wilson Agyapong, Junqing Liu, Maximilian Fuchs, Ke Xiao, Christopher Jahn, Reto Eggenschwiler, Tobias Cantz, Julia Beimdiek, Falk F. R. Buettner, Theresia Kraft, Jan Hegermann, Ivonne J. Knorr, Lisa Ernst, Linda Feldbrügge, Resa Puffert, Kevin Schmidt, Christian Bär, Jeannine Hoepfner, Thomas Thum   +24 more
wiley   +1 more source