Results 11 to 20 of about 2,373 (141)

Comparison of intrauterine transfusion techniques in hemolytic disease of the fetus and newborn. [PDF]

open access: yesUltrasound Obstet Gynecol
ABSTRACT Objectives Intrauterine transfusions (IUTs) are the cornerstone in treatment for hemolytic disease of the fetus and newborn (HDFN). It has been suggested that a non‐vascular intraperitoneal blood transfusion used in conjunction with an intravascular IUT can slow the decrease in fetal hemoglobin (Hb) levels, potentially extending the interval ...
van 't Oever RM   +8 more
europepmc   +2 more sources

Yolk sac development, function and role in rodent pregnancy

open access: yesBirth Defects Research, Volume 115, Issue 14, Page 1243-1254, August 15, 2023., 2023
Abstract During the early phases of embryonic development, the yolk sac serves as an initial placenta in many animal species. While in some, this role subsides around the end of active organogenesis, it continues to have important functions in rodents, alongside the chorio‐allantoic placenta.
Asher Ornoy, Richard K. Miller
wiley   +1 more source

Symphony in the crowd: Key genetic alterations in prostate cancer

open access: yesCancer Innovation, Volume 2, Issue 3, Page 203-209, June 2023., 2023
Genetic alterations in prostate cancer (PCa). PCa progresses from a recurrent inflammation of the prostatic epithelia to an aggressive form. The key genetic alterations during this conversion include: altered androgen receptor (AR), gene fusion, alteration of tumor suppressors, defective DNA repair mechanism.
Neshat Masud
wiley   +1 more source

An intriguing case of a paravertebral extramedullary erythropoiesis presenting as tumor‐mimicking lesion in a patient with eosinophilia with FIP1L1‐PDGFRA rearrangement

open access: yesClinical Case Reports, Volume 10, Issue 12, December 2022., 2022
This is the first reported case of extramedullary hematopoiesis interesting only one cell lineage (erythrocytes) presenting as an isolated tumor‐like lesion in the posterior mediastinum in a 28‐year‐old man with a 13‐year history of eosinophilia with FIP1L1‐PDGFRA fusion gene successfully surgically treated. Abstract Extramedullary hematopoiesis in the
Sassi Farah   +6 more
wiley   +1 more source

LRFN2 binding to NMDAR inhibits the progress of ESCC via regulating the Wnt/β‐Catenin and NF‐κB signaling pathway

open access: yesCancer Science, Volume 113, Issue 10, Page 3566-3578, October 2022., 2022
Our results indicate that LRFN2 binding to NMDARs inhibits ESCC’ progression through regulating the Wnt/β‐catenin pathway and NF‐kB pathway, which provides a novel antitumor target to improve the lifetime of ESCC patients. Abstract As a neuronal transmembrane protein, leucine‐rich repeat and fibronectin type‐III domain‐containing protein 2 (LRFN2) can ...
Yu Zhou   +9 more
wiley   +1 more source

Noninvasive prenatal diagnosis of fetal RhD status using cell-free fetal DNA in maternal plasma with TaqMan® real-time PCR assay [PDF]

open access: yes, 2007
Prenatal diagnosis is now part of established obstetric practice in many countries. However, conventional methods of prenatal diagnosis of obtaining fetal tissues for genetic analysis, including amniocentesis and chorionic villus sampling, are invasive
Rekhviashvili, Tea
core   +1 more source

Fetal‐placental antigens and the maternal immune system: Reproductive immunology comes of age*

open access: yesImmunological Reviews, Volume 308, Issue 1, Page 25-39, July 2022., 2022
Abstract Reproductive physiology and immunology as scientific disciplines each have rich, largely independent histories. The physicians and philosophers of ancient Greece made remarkable observations and inferences to explain regeneration as well as illness and immunity.
Margaret G. Petroff   +2 more
wiley   +1 more source

Maternal mirror syndrome with foetal hydrops due to isoimunization by anti‐KPa antibodies: A case report and narrative literature review

open access: yesClinical Case Reports, Volume 10, Issue 2, February 2022., 2022
The association of fetal hydrops with maternal edema should prompt the suspicion of mirror syndrome. In the consideration of fetal hydrops, it is important to include immunohematological studies that rule out the presence of rare antibodies. Abstract We present a rare case of mirror syndrome due to anti‐Kpa antibodies, which can be difficult to ...
Juan Pina Moreno   +3 more
wiley   +1 more source

Cyclin‐Dependent Kinase 1 Inhibition Potentiates the Proliferation of Tonsil‐Derived Mesenchymal Stem Cells by Delaying Cellular Senescence

open access: yesStem Cells International, Volume 2022, Issue 1, 2022., 2022
Mesenchymal stem cells (MSCs) have been widely used in tissue regeneration and stem cell therapy and are currently being tested in numerous clinical trials. Senescence‐related changes in MSC properties have attracted considerable attention. Senescent MSCs exhibit a compromised potential for proliferation; senescence acts as a stress response that ...
Da Hyeon Choi   +3 more
wiley   +1 more source

Unannotated single nucleotide polymorphisms in the TATA box of erythropoiesis genes show in vitro positive involvements in cognitive and mental disorders

open access: yesBMC Medical Genetics, 2020
Background Hemoglobin is a tetramer consisting of two α-chains and two β-chains of globin. Hereditary aberrations in the synthesis of one of the globin chains are at the root of thalassemia, one of the most prevalent monogenic diseases worldwide.
Mikhail Ponomarenko   +8 more
doaj   +1 more source

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