Results 81 to 90 of about 15,198 (251)

The Role of Immune System in Thalassemia Major: A Narrative Review

Journal of Pediatrics Review, 2018
Context: Thalassemia is a genetic disorder of hemoglobin production. Patients with thalassemia major (TM) require regular blood transfusions to keep a compatible hemoglobin level for oxygenating organs.  These patients suffer from different complications
Ali Bazi, Iraj Shahramian, Hajar Yaghoobi, Majid Naderi, Hakim Azizi   +4 more
doaj  

Protective Vaccination Reshapes Hepatic Response to Blood-Stage Malaria of Genes Preferentially Expressed by NK Cells

Vaccines, 2020
The role of natural killer (NK) cells in the liver as first-line post infectionem (p.i.) effectors against blood-stage malaria and their responsiveness to protective vaccination is poorly understood.
Marcos J. Araúzo-Bravo, Denis Delic, Daniela Gerovska, Frank Wunderlich   +3 more
doaj   +1 more source

EGFRvIV: a previously uncharacterized oncogenic mutant reveals a kinase autoinhibitory mechanism [PDF]

, 2010
Tumor cells often subvert normal regulatory mechanisms of signal transduction. This study shows this principle by studying yet uncharacterized mutants of the epidermal growth factor receptor (EGFR) previously identified in glioblastoma multiforme, which ...
AJ Ekstrand, AJ Wong, AW Burgess, CT Kuan, DB Ramnarain, E Tzahar, ER Wood, F Chiara, F M White, G Chiosis, G Getz, G Pines, HK Gan, HK Shu, J Jeuken, J Stamos, J Wykosky, JJ Li, JP Dawson, K Shtiegman, L Frederick, LM Shewchuk, M Katz, M Ladanyi, M Landau, M Nagane, MJ McManus, N Gotoh, N Jura, NE Hynes, P H Huang, PH Huang, PH Huang, R Zenz, RW Clarkson, S Hafizi, S Pulciani, SJ Lavictoire, T Shimamura, WG An, X Zhang, Y Yarden, Y Zhang, Y Zwang   +43 more
core   +1 more source

Capsaicin‐mediated repair of circadian disruption‐induced Intestinal barrier damage via the gut microbiota

Food Frontiers, Volume 5, Issue 6, Page 2579-2590, November 2024.
1. Capsaicin (CAP) supplementation mitigated the negative effects of circadian disruption on the intestinal barrier in mice. 2. CAP supplementation restored the normal expression of circadian clock genes in mice liver and colon. 3. CAP supplementation positively influenced the gut microbiota, restoring its diversity and rhythmic fluctuations altered by
Yupei Deng, Bolin Lin, Chi‐Tang Ho, Jie Xiao, Yong Cao, Jun‐qing Huang, Muwen Lu   +6 more
wiley   +1 more source

Can we safely stop testing for Rh status and immunizing Rh-negative women having early abortions? A comparison of Rh alloimmunization in Canada and the Netherlands

Contraception: X, 2019
Objective: The objective of this study was to compare Rh alloimmunization rates in two countries (Canada and the Netherlands) with completely different policies regarding abortion-related use of anti-D immunoglobulin to ultimately determine any benefit ...
Ellen R. Wiebe, Mackenzie Campbell, Abigail R.A. Aiken, Arianne Albert   +3 more
doaj   +1 more source

Peculiarities of Blood Group Distribution among Infants Born to Mothers with Negative Rh-Factor (Findings of 2014) [PDF]

, 2016
Our works consider the investigation of possible manifestation of hyperbilirubinemia in infants against the ground of genetic incompatibilities of the fetus according to АВ0 system and Rh-factor (D) concerning the maternal organism.
Cherniukh, O.G.
core  

Getting in the zone: Metabolite transport across liver zones

Acta Physiologica, Volume 240, Issue 11, November 2024.
Abstract The liver has many functions including the regulation of nutrient and metabolite levels in the systemic circulation through efficient transport into and out of hepatocytes. To sustain these functions, hepatocytes display large functional heterogeneity.
Stan F. J. van de Graaf, Coen C. Paulusma, Wietse In het Panhuis   +2 more
wiley   +1 more source

Pregnant women's knowledge and clinical management of hemolytic disease of the fetus and newborn in Pará, Brazil

Hematology, Transfusion and Cell Therapy
Objective: To evaluate the knowledge of pregnant women and the clinical management of hemolytic disease of the fetus and newborn, as well as to describe the gestational profile, risk factors and socio-epidemiological profile of pregnant women treated at ...
Jhemily de Nazaré Gonçalves e Silva, Andrya Maia de Souza, Fabiane Monteiro do Rosario, Laine Celestino Pinto   +3 more
doaj   +1 more source

Hemolytic Disease of the Newborn: A Review of Current Trends and Prospects

Pediatric Health, Medicine and Therapeutics, 2021
Akshay Kiran Myle,1,2 Ghanim Hamid Al-Khattabi2 1Department of Clinical Research, General Medicine, Pharmacology, Integrative Medicine, Clinical Researcher.
Myle AK, Al-Khattabi GH
doaj  

Avaliação da hemorragia feto-materna em puérperas com indicação para ministração de imunoglobulina anti-D Evaluation of fetomaternal hemorrhage in postpartum patients with indication for administration of anti-D immunoglobulin

Cadernos de Saúde Pública, 2005
Avaliamos a ocorrência da hemorragia feto-materna entre 343 puérperas que receberiam profilaxia da aloimunização Rh com emprego de imunoglobulina anti-D.
Eduardo Baiochi, Luiz Camano, José Orlando Bordin   +2 more
doaj   +1 more source