Results 141 to 150 of about 29,567 (256)

Clostridium perfringens α-toxin impairs erythropoiesis by inhibition of erythroid differentiation

Scientific Reports, 2017
Clostridium perfringens α-toxin induces hemolysis of erythrocytes from various species, but it has not been elucidated whether the toxin affects erythropoiesis.
Teruhisa Takagishi, Masaya Takehara, Soshi Seike, Kazuaki Miyamoto, Keiko Kobayashi, Masahiro Nagahama   +5 more
doaj   +1 more source

c-Maf is indispensable for the microenvironment of definitive erythropoiesis as it forms erythroblastic islands in fetal liver [PDF]

, 2011
Thesis (Ph. D. in Medical Sciences)--University of Tsukuba, (A), no.
日下部 学
core  

Altered Chromatin Occupancy of Master Regulators Underlies Evolutionary Divergence in the Transcriptional Landscape of Erythroid Differentiation [PDF]

, 2014
Erythropoiesis is one of the best understood examples of cellular differentiation. Morphologically, erythroid differentiation proceeds in a nearly identical fashion between humans and mice, but recent evidence has shown that networks of gene expression ...
An, Xiuli, Lacy, Jessica N., Mikkelsen, Tarjei S., Mohandas, Narla, Sankaran, Vijay G., Ulirsch, Jacob C.   +5 more
core   +2 more sources

Cytotoxic activities of CD8+ T cells collaborate with macrophages to protect against blood-stage murine malaria

eLife, 2015
The protective immunity afforded by CD8+ T cells against blood-stage malaria remains controversial because no MHC class I molecules are displayed on parasite-infected human erythrocytes.
Takashi Imai, Hidekazu Ishida, Kazutomo Suzue, Tomoyo Taniguchi, Hiroko Okada, Chikako Shimokawa, Hajime Hisaeda   +6 more
doaj   +1 more source

Humanized Culture Medium for Clinical Expansion of Human Erythroblasts

Cell Transplantation, 2010
Ex vivo-generated erythroblasts represent alternative transfusion products. However, inclusion of bovine components in media used for their growth precludes clinical use, highlighting the importance of developing culture media based on pharmaceutical ...
Giovanni Migliaccio, Massimo Sanchez, Francesca Masiello, Valentina Tirelli, Lilian Varricchio, Carolyn Whitsett, Anna Rita Migliaccio   +6 more
doaj   +1 more source

Metabolic reprogramming during ineffective erythropoiesis in β-thalassemia/HbE disease

Experimental and Molecular Pathology
Ineffective erythropoiesis, the main cause of anemia in β-thalassemia disease, is characterized by dramatic expansion of erythroblasts and increased erythroblast cell death.
Chanyanat Sukhuma, Donny Nauphar, Khanita Nuamsee, Wasinee Kheansaard, Kittiphong Paiboonsukwong, Alisa Wilantho, Chumpol Ngamphiw, Pornthip Chaichompoo, Sissades Tongsima, Saovaros Svasti, Phatchariya Phannasil   +10 more
doaj   +1 more source

Erythroblast enucleation at a glance

Journal of Cell Science
ABSTRACT Erythroid enucleation, the penultimate step in mammalian erythroid terminal differentiation, is a unique cellular process by which red blood cells (erythrocytes) remove their nucleus and accompanying nuclear material. This complex, multi-stage event begins with chromatin compaction and cell cycle arrest and ends with generation ...
Lucas M. Newton, Velia M. Fowler, Patrick O. Humbert   +2 more
openaire   +2 more sources

Tyrosine kinase receptor RON functions downstream of the erythropoietin [PDF]

, 2004
Erythropoietin (EPO) is required for cell survival during differentiation and for progenitor expansion during stress erythropoiesis. Although signaling pathways may couple directly to docking sites on the EPO receptor (EpoR), additional
Akker, E. (Emile) van den, Dijk, T.B. (Thamar) van, Grossmann, K.S., Lindern, M.M. (Marieke) von, Löwenberg, B. (Bob), Parren-Van Amelsvoort, M. (Martine), Schaeper, U., Toney-Earley, K., Waltz, S.E.   +8 more
core  

Mice deficient in the putative phospholipid flippase ATP11C exhibit altered erythrocyte shape, anemia, and reduced erythrocyte life span

, 2014
Transmembrane lipid transporters are believed to establish and maintain phospholipid asymmetry in biological membranes; however, little is known about the in vivo function of the specific transporters involved.
Bröer, Stefan, Coupland, Lucy A, Cromer, Deborah, D'Rozario, James, Enders, Anselm, Kirk, Kiaran, Parish, Christopher, Teoh, Narci C, Winterberg, Markus, Yabas, Mehmet   +9 more
core   +1 more source

Garland of Erythroblasts Around Macrophage: The Erythroblastic Island

Turkish Journal of Hematology, 2019
Chandan Kumar, Garima Jain, Anita Chopra
openaire   +3 more sources