Results 61 to 70 of about 299,972 (305)

Erythrocyte oxidative stress in clinical management of diabetes and its cardiovascular complications

, 2007
Diabetes mellitus is a chronic disease in its own right and is also regarded as a cardiovascular risk factor as well as a cardiovascular disease, due to its ability to progress to a stage of cardiovascular co-morbidity.
Jelinek, H. F., Richards, R. S., Kerr, P. G., Nwose, E. U.   +3 more
core   +1 more source

Effects of Add‐On Icosapent Ethyl With Standard Treatment on Functional Outcomes and Inflammatory Biomarkers in Acute Ischemic Stroke: A Blinded Randomized Controlled Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Ischemic stroke, a major cause of mortality and long‐term disability, results from the abrupt cessation of cerebral blood flow due to vascular occlusion or rupture. Icosapent Ethyl (EPA‐EE), approved for hypertriglyceridemia, has anti‐inflammatory and antithrombotic properties that may lessen ischemic damage.
Mitra Mahmoudi Meymand, Seyed Hossein Aghamiri, Saeed Mohmammad Soleymani, Shadiyeh Bararpoor Poshkohi, Samaneh Masoudi, Hadi Esmaily   +5 more
wiley   +1 more source

Developing and Evaluating a Laboratory‐Based Frailty Index for the Prediction of Long‐Term Health Outcomes in Systemic Lupus Erythematosus

Arthritis Care &Research, EarlyView.
Objective We aimed to construct and evaluate the first laboratory‐based frailty index (FI‐Lab) for predicting adverse outcomes in systemic lupus erythematosus (SLE) and to compare its predictive ability to that of an existing clinical FI. Methods We used data from a single‐center prospective cohort of adult patients with SLE whose baseline visit ...
Grace Burns, Samuel D. Searle, Alexandra Legge   +2 more
wiley   +1 more source

Effect of Thioridazine on Erythrocytes [PDF]

Toxins, 2013
Background: Thioridazine, a neuroleptic phenothiazine with antimicrobial efficacy is known to trigger anemia. At least in theory, the anemia could result from stimulation of suicidal erythrocyte death or eryptosis, which is characterized by cell shrinkage and by phospholipid scrambling of the cell membrane with phosphatidylserine exposure at the ...
Lang, E., Modicano, P., Arnold, M., Bissinger, R., FAGGIO, Caterina, Abed, M., Lang, F.   +6 more
openaire   +6 more sources

Associations of Rheumatoid Arthritis Disease Activity With Frailty Over Five Years of Follow‐up

Arthritis Care &Research, EarlyView.
Objective To evaluate whether rheumatoid arthritis (RA) disease activity is associated with frailty both in cross‐section and longitudinally. Methods Participants within the Veterans Affairs Rheumatoid Arthritis (VARA) registry enrolled from 2003 to 2022 were included.
Courtney N. Loecker, Yangyuna Yang, Punyasha Roul, Aaron Baraff, Myra S. Schmaderer, Lani Zimmerman, Kaleb Michaud, Namrata Singh, Grant W. Cannon, Gary Kunkel, Ted R. Mikuls, Ariela R. Orkaby, Joshua F. Baker, Bryant R. England, Katherine D. Wysham   +14 more
wiley   +1 more source

The C-terminal portion of the cleaved HT motif is necessary and sufficient to mediate export of proteins from the malaria parasite into its host cell [PDF]

, 2013
The malaria parasite exports proteins across its plasma membrane and a surrounding parasitophorous vacuole membrane, into its host erythrocyte. Most exported proteins contain a Host Targeting motif (HT motif) that targets them for export. In the parasite
Thalassinos, Konstantinos, Tarr, Sarah J., Osborne, Andrew R., Cryar, Adam, Haldar, K.   +4 more
core   +1 more source

Structural Alterations of Human Erythrocytes Induced by Minocycline

Cells
The non-antibacterial effects of the tetracycline antibiotic minocycline on human erythrocytes are currently under investigation. Our data indicate alterations in the surface structure of erythrocytes; the antibiotic promotes the redistribution of ...
Elena Baeva, Marina Holyavka, Valery Artyukhov, Maxim Kondratyev   +3 more
doaj   +1 more source

Interactions Between Aerolysin, Erythrocytes, and Erythrocyte Membranes [PDF]

Infection and Immunity, 1975
Aerolysin, a hemolytic and lethal exotoxin of Aeromonas hydrophila , was analyzed for amino acids. Assuming 8 histidine residues/mol, the purified toxic protein has, by summation, a molecular weight of 49,000, a value in agreement with earlier estimates by other methods.
A W, Bernheimer, L S, Avigad, G, Avigad
openaire   +2 more sources

Association of Elevated Platelets and C‐Reactive Protein With Severe Disease and Poor Survival in Systemic Sclerosis

Arthritis Care &Research, EarlyView.
Objective Elevated C‐reactive protein (CRP) levels in systemic sclerosis (SSc) have been linked with severe disease and worse survival, but the role of platelet levels remains unclear. This study examined whether elevated platelet levels, CRP levels, or both are associated with disease severity, progression, and survival in SSc.
Brian S. Lee, Shufeng Li, Srijana Davuluri, Jennifer Lee, Lorinda Chung   +4 more
wiley   +1 more source

FROM ANIMAL HIBERNATION TO HUMAN’S HYPOMETABOLISM: CELLULAR MECHANISMS OF NATURAL AND ARTIFICIAL HYPOBIOSIS

Український антарктичний журнал, 2018
Objective: to carry out a comparative study of structural and functional responses of rats and hamsters RBCs when the animals entered and left an artificial hypobiosis state under conditions of hypothermia-hypoxia-hypercapnia.
S. V. Repina, O. A. Nardid, O. V. Shylo, I. F. Kovalenko   +3 more
doaj   +1 more source