Results 61 to 70 of about 526,880 (360)

Erythrocyte aggregation and metabolic syndrome

open access: yes, 2014
Erythrocyte aggregation has been consistently associated with insulin resistance, central obesity and hypertension in the literature. Oxidative stress and chronic inflammation are almost always present in metabolic syndrome (MetS).
Tinley, Paul   +3 more
core   +1 more source

Disease progression in Plasmodium knowlesi malaria is linked to variation in invasion gene family members. [PDF]

open access: yes, 2014
Emerging pathogens undermine initiatives to control the global health impact of infectious diseases. Zoonotic malaria is no exception. Plasmodium knowlesi, a malaria parasite of Southeast Asian macaques, has entered the human population. P.
Paul C. Divis (615586)   +90 more
core   +1 more source

Erythrocyte morphology in metabolic syndrome

open access: yes, 2012
The study of erythrocyte morphology is of great importance in the field of hemorheology as the deformability of the circulating cells has a fundamental influence on the rheological properties of the blood.
Nwose, Ezekiel Uba   +2 more
core   +1 more source

BASIGIN is a receptor essential for erythrocyte invasion by Plasmodium falciparum

open access: yesNature, 2011
Erythrocyte invasion by Plasmodium falciparum is central to the pathogenesis of malaria. Invasion requires a series of extracellular recognition events between erythrocyte receptors and ligands on the merozoite, the invasive form of the parasite. None of
Cécile Crosnier   +11 more
semanticscholar   +1 more source

Efficacy and Safety Analysis of Roxarestat in Regulating Renal Anemia in Patients on Maintenance Hemodialysis

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley   +1 more source

The association of dyslipidemia with erythrocyte aggregation

open access: yes, 2015
Aim: The present study aims to associate erythrocyte aggregation with plasma lipid concentration. Materials & Methods: Ninety-nine participants were divided into two groups: normolipidemic and dyslipidemic.
Nwose, Ezekiel Uba   +3 more
core   +1 more source

Structure of malaria invasion protein RH5 with erythrocyte basigin and blocking antibodies

open access: yesNature, 2014
Invasion of host erythrocytes is essential to the life cycle of Plasmodium parasites and development of the pathology of malaria. The stages of erythrocyte invasion, including initial contact, apical reorientation, junction formation, and active ...
Katherine E. Wright   +11 more
semanticscholar   +1 more source

Erythrocyte Protoporphyrin [PDF]

open access: yesBlood, 1972
Abstract Blood protoporphyrin (PROTO) concentration in man and animals has been studied as a possible means of assessing the relationship between iron supply and marrow requirements. There appear to be two fractions of PROTO: one at a level of about 30 µg/ 100 ml unrelated to either iron supply or cell age, and a second fraction that ...
E E, Langer   +5 more
openaire   +2 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

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