Results 191 to 200 of about 97,183 (266)

Risk factors for progression to bronchitis or pneumonia in hospitalized children with human rhinovirus infection: a retrospective cohort study using machine learning. [PDF]

Front Pediatr
Dai Q, Zhou J, Chen Y, Ye Q.
europepmc   +1 more source

Synergistic p53 Pathway Activation Through Sono‐Gene Therapy Induced by Ultrasound‐Triggered Theranostic Mesoporous Nanoparticles

Advanced Science, EarlyView.
Schematic representation of ultrasound‐mediated ICG/siCD24@MSN‐LCD from nanostructure to synergistic sono‐gene therapy. This nanoplatform targets ASGPR via the LCD shell, which dissociates to release loaded ICG and siCD24. The core mechanism involves ultrasound‐guided sonodynamic therapy by ICG and CD24 knockdown by siCD24, both activating the p53 axis
Yading Zhao, Lu Guo, Dandan Shi, Xiao Sun, Mengmeng Shang, Song Ning, Shuting Huang, Xiaoxuan Wang, Rui Liu, Yuye Fu, Suyun Li, Jie Li   +11 more
wiley   +1 more source

GM‐CSF Promotes Neutrophil PD‐L1 Expression Through the VEGFR‐2/STAT6/CSF2 Signaling Axis in Oral Squamous Cell Carcinoma

Advanced Science, EarlyView.
VEGFR‐2 signaling in OSCC activates Src–STAT6‐dependent CSF2 transcription, driving tumor‐derived GM‐CSF secretion. GM‐CSF programs neutrophils to express PD‐L1 through STAT5–mTOR/S6K signaling, suppressing cytotoxic CD8+ T cells. This pathway reveals a tumor–neutrophil immune checkpoint circuit that limits anti‐PD‐1 responsiveness in OSCC.
Fangxing Zhu, Yuanhe You, Yiyi Zhang, Yibin Dai, Xinyu Zhou, Yong Fu, Xi Lu, Yingying Huang, Zhihang Zhou, Ronghui Xia, Wutong Ju, Zhaoqi Yuan, Laiping Zhong, Tongchao Zhao   +13 more
wiley   +1 more source

Xinfeng Capsule combined with conventional Western medicine for rheumatoid arthritis: Efficacy, safety, and subgroup analysis in a multicenter real-world study. [PDF]

Medicine (Baltimore)
Yang J, Zhang S, Liu J, Xin L, Lu S.
europepmc   +1 more source

Engineered Xenogeneic Bone Scaffold with IL‐10 Nanodelivery System: Immunomodulation and BMSC Fate Programming for Skull Defect Repair

Advanced Science, EarlyView.
A multifunctional regenerative composite is constructed by 3D‐printing thermosensitive PNIPAM hydrogel embedded with MPDA@IL‐10 nanoparticles and autologous BMSCs onto antigen‐depleted porcine bone matrix for beagle critical‐sized skull defect reconstruction.
Weihao Lv, Lei Zhang, Fei Fei, Zhibin Wu, Xiuquan Wu, Ya‐nan Dou, Yihao Fu, Hao Chang, Yujie Qiang, Huaxia Xie, Ni An, Leiying Chen, Hongchen Zhang, Min‐Wen Zheng, Hongqing Chen, Xia Li, Zhou Fei   +16 more
wiley   +1 more source

A hemorheological perspective on coronary microvascular dysfunction: Association of erythrocyte parameters with angiography-derived coronary microcirculatory resistance. [PDF]

PLoS One
AlQazzaz A, Lu Y, Bao JY, Mintz GS, Feng J, Zhang Y, Gao S, Song Q, Ning F, Al-Samawi HH, Al-Manj M, Al-Asadi M, Huang X, Guo N.   +13 more
europepmc   +1 more source

Radiographic outcome over 15 years in patients with early rheumatoid arthritis - a BARFOT-study. [PDF]

BMC Rheumatol
Andersson MLE, Hafström I, Forslind K.
europepmc   +1 more source

Red Blood Cell Fragmentation Mimicking Platelet Recovery in a Patient With Severe Pneumonia. [PDF]

Clin Case Rep
Shi D, Dong Z.
europepmc   +1 more source

Neutrophil CD64, CD66b, and Serum Thioredoxin as Early Biomarkers of Delayed Fracture-Related Infection After Internal Fixation: A Prospective Cohort Study. [PDF]

Cureus
Ali S, Siddiqui S, Singh A, Yadav M, Ali A, Ul Haq R, Mehdi AA.   +6 more
europepmc   +1 more source

Predictive Potential of Red Blood Cell Distribution Width and Platelet Ratio (RDW/PLT) in Early Pregnancy Loss. [PDF]

Int J Womens Health
Ateş Ç, Bakırcı M.
europepmc   +1 more source