Significant Associations Between Blood Cell Counts and Plasma Cytokines, Chemokines, and Growth Factors. [PDF]
Eriksson LB+3 more
europepmc +1 more source
Vascular smooth muscle cells (VSMCs)‐specific deficiency of PP2Acα exacerbates aortic aneurysm and dissection (AAD) by promoting phenotypic switching through AKT1‐mediated phosphorylation and stabilization of Kruppel‐like factor 4 (KLF4). Reduced PP2Acα enhances KLF4 ubiquitination resistance, suppressing VSMC contractile genes and accelerating aortic ...
Wei‐Peng Hu+7 more
wiley +1 more source
Association Between Thymosin β4 and Coronary Arterial Lesions in Children with Kawasaki Disease. [PDF]
Wu J+6 more
europepmc +1 more source
Advanced Pharmaceutical Nanotechnologies Applied for Chinese Herbal Medicines
This review offers a comprehensive overview of pharmaceutical nanotechnology strategies to address limitations associated with the complex material basis and relative mild therapeutic efficacy of Chinese herbal medicines, and summarizes the advantages of these strategies.
Jiameng Li+11 more
wiley +1 more source
Infections in foot and ankle bone surgery: Comparison between single- and multiday use of postoperative oral antibiotics. [PDF]
Shin WJ+8 more
europepmc +1 more source
Leukocyte Count, Erythrocyte Sedimentation Rate, and Diabetes Incidence in a National Sample of US Adults [PDF]
Earl S. Ford
openalex +1 more source
Wound infections induce gcFGF8a expression, which subsequently executes direct antimicrobial activity to suppress local infection while simultaneously activating the FGFR4‐mediated ERK/AKT‐mTOR signaling cascade, thereby upregulating HIF1α and enhancing glycolysis. These coordinated actions synergistically promote tissue repair by eliminating pathogens
Ya‐Zhen Hu+6 more
wiley +1 more source
Risk factors for mortality in anti-MDA5 antibody-positive dermatomyositis with interstitial lung disease: a systematic review and meta-analysis. [PDF]
Yang Y+5 more
europepmc +1 more source
A phosphorothioate‐modified aptamer PTf‐SRiApt capable of disrupting “undruggable” transcription factor SCAF4‐POLR2A interaction with high inhibitory activity and biological stability is presented here. Through this inhibition, PTf‐SRiApt successfully arrested cell cycle progression, induced cell death, and elevated immune recruitment in SCAF4‐POLR2A ...
Liyan Fei+13 more
wiley +1 more source
Clinical prediction of intravenous immunoglobulin-resistant Kawasaki disease based on interpretable Transformer model. [PDF]
Chen G, Yang Z.
europepmc +1 more source