Results 221 to 230 of about 648,885 (308)

Peripheral blood cell counts of prematurely born, small for gestational age neonates. [PDF]

Clin Exp Pediatr
Zuiderwijk MO, Groene S, Lopriore E, Bekker V, Schoenaker MHD.   +4 more
europepmc   +1 more source

Ultrasound‐Activated Nanoinhibitors Blocking the Chemo‐Immune Checkpoint to Overcome Chemotherapy‐Induced Immune Resistance

Advanced Science, EarlyView.
A sono‐responsive chemo‐immune checkpoint nanoinhibitor (Sono‐TT8) co‐delivering TPZ chemotherapy and siXkr8 simultaneously kills tumor cells and blocks PS externalization, reversing chemotherapy‐induced immunosuppression and enhancing antitumor immunity. ABSTRACT Breast cancer features an immunosuppressive tumor microenvironment following chemotherapy
Yunfan Liu, Chier Du, Leilei Zhu, Hongjin An, Shengzhe Hou, Yi Lan, Xuemei Tang, Min Xu, Peng Luo, Hua Teng, Hao Yang, Xun Guo, Jianli Ren, Zhiyi Zhou   +13 more
wiley   +1 more source

Discriminating Osteoarticular Infection Bacterial Aetiology Using Immune-Inflammatory Biomarkers. [PDF]

Microorganisms
Fortunato M, Tabard-Fougère A, Paris E, De Marco G, Vazquez O, Steiger C, Ramadani A, Tsoupras A, Dayer R, Ceroni D.   +9 more
europepmc   +1 more source

Supramolecular Zinc–Polyphenol Coordination Assemblies Mitigate Colonic Inflammation by Regulating Mucosal Barrier and Microbiome

Advanced Science, EarlyView.
A carrier‐free zinc‐coordinated polyphenol nanoplatform (ZnCA NPs) is designed as an “all‐in‐one” therapeutic strategy for intestinal inflammation. The ZnCA NPs exhibit enhanced colonic accumulation and broad‐spectrum reactive oxygen and nitrogen species scavenging.
Qiwen Xie, Mai Ye, Xuexia Liu, Jing Wang, Ying Chen, Lu Tan, Jinheng Fu, Xiaochang Huang   +7 more
wiley   +1 more source

Early Postoperative Inflammatory Responses Following Primary Total Hip Arthroplasty Using Different Antibiotic-Loaded Bone Cement Formulations: A Prospective Observational Cohort Study. [PDF]

J Clin Med
Ion NCI, Fleaca SR, Bocea BA, Mohor CI, Roman MD, Mohor CI, Diconi AF, Turcu A, Tutuianu II, Faur M, Veres VM, Vereș VV, Birlutiu V.   +12 more
europepmc   +1 more source

Multifunctional Nanovaccine‐Radiotherapy Synergy Drives Anti‐Tumor Immunity via Multi‐Cascade Cell Death for Pancreatic Cancer Therapy

Advanced Science, EarlyView.
Machine‐learning‐driven transcriptomic analysis identifies FSTL3 as a key tumor‐microenvironment regulator in desmoplastic pancreatic adenocarcinoma. A cRGD‐modified liposome co‐loading gemcitabine and siFSTL3 serves as an irradiation‐triggered in situ nanovaccine. It synergizes with radiotherapy to induce ferroptosis and immunogenic cell death through
Chengyi Huang, Yushu Han, Xiang Liu, Chuanhao Wang, Xiaofei Zhu, Di Chen, Yangyang Gong, Liang Chen, Wenjuan Chen, Zhenyuan Miao, Bufu Tang, Huojun Zhang   +11 more
wiley   +1 more source

Association of reperfusion delay with inflammatory markers and coronary flow impairment assessed by corrected TIMI frame count in STEMI patients undergoing primary PCI: a cohort study. [PDF]

Am J Cardiovasc Dis
Nia RA, Safi M, Meigoli MSS, Namazi MH, Kooshamoghadam V, Fadaeihaghi K, Taghipour S, Motlagh PM, Shayegh ZS, Ghanouni S, Safari M, Azhdarimoghaddam A, Bahmanpour M, Khosravi F, Pourmohammadi N, Ramezanipour S, Azar SM, Khorsand K.   +17 more
europepmc   +1 more source

The GPX3‐VCAM1 Axis Gates Pro‐Fibrotic Tubule Cell Fate in Hyperuricemic Nephropathy

Advanced Science, EarlyView.
Hyperuricemia induces NLRP3 inflammasome signaling activation and downregulation of GPX3 in proximal tubular epithelial cells, leading to oxidative stress–driven VCAM1 upregulation, emergence of pro‐fibrotic proximal tubule cells, macrophage recruitment, and renal fibrosis.
Yunfei Qi, Qiang Zhao, Yue Lve, Yaming Yuan, Tingting Zhou, Yue Yuan, Dexi Wu, Yifan Tang, Yan Liu, Zhigang Li, Chunping Jiang, Qiurong Ding   +11 more
wiley   +1 more source

Post-IVIG Aseptic Meningitis in a Pediatric Patient With Kawasaki Disease: A Case Report. [PDF]

Cureus
Kheir S, Elouali A, Sara A, Rkain M, Babakhouya A.   +4 more
europepmc   +1 more source

Mapping Embryonic Mouse Lung Development Using Enhanced Spatial Transcriptomics

Advanced Science, EarlyView.
The mammalian lung contains ∼50 cell types arranged along the airway epithelium. Here, deterministic barcoding sequencing (DBiT‐seq) is optimized to nearly double transcript recovery, enabling highly sensitive spatial mapping of the embryonic mouse lung.
Pengfei Zhang, Benjamin K. Law, Niles Huang, Katharine Goodwin, Celeste M. Nelson, Michelle M. Chan   +5 more
wiley   +1 more source