Boosting Sensory Nerve‐to‐Bone Interactions Enhances Hedgehog Mediated Calvarial Bone Repair
Boosting sensory nerve activity via TrkA agonism strongly accelerates calvarial bone repair in adult mice. Furthermore, single‐cell RNA sequencing and neuron–bone interactome analyses identify these sensory neurons as a direct neural source of Hedgehog pathway ligands. Consequently, these ligands drive osteoblast differentiation of skeletal progenitors,
Zhao Li +9 more
wiley +1 more source
Integrated ESR and PLT-H Measurement Using the BC-6800 Plus Hematology Analyzer: A Comprehensive Analytical Evaluation. [PDF]
Chen M, Yan J, Ye M, Zhang S, Zheng X.
europepmc +1 more source
Engineering Oncolytic Virus‐Armed Macrophages for Enhanced Cancer Immunotherapy
ZIFOA‐M is engineered by conjugating oncolytic adenovirus‐loaded ZIF‐8 nanoparticles onto macrophage surfaces via bioorthogonal chemistry. Upon tumor infiltration, the platform releases OA to downregulate CD47/CD24 on tumor cells, restoring macrophage phagocytosis.
Jilong Wang +10 more
wiley +1 more source
Genome-Wide Association Studies for 24 Hematological Traits in Production Pigs Before and After Weaning. [PDF]
Sun J +8 more
europepmc +1 more source
Evaluation of red cell distribution width in dogs with pulmonary hypertension [PDF]
Connolly, D J +5 more
core +1 more source
NET‐DNA is enriched during early endometriotic lesion establishment and drives anoikis resistance by promoting an ANXA2–TMEM215–BiP axis. This pathway strengthens ER–mitochondria contacts, enhances PINK1/Parkin‐associated mitophagy, preserves mitochondrial homeostasis, and supports ectopic stromal cell survival, thereby facilitating lesion persistence ...
Honglin Wang +12 more
wiley +1 more source
Predictors of Shoulder Pathology in Rheumatoid Arthritis: A Cross-Sectional Study. [PDF]
Kumar R, Kumar G, Singh A, Akhtar MJ.
europepmc +1 more source
This study presents an injectable DNA‐based porous hydrogel integrating catechol motifs and targeting aptamers for pulpitis management. Upon in situ crosslinking, the scaffold actively recruits endogenous dental pulp stem cells, restores redox homeostasis, and modulates immune responses.
Luhui Cai +9 more
wiley +1 more source
Posterior percutaneous fixation without anterior or posterior debridement for infectious spondylitis in high-morbidity patients: A retrospective comparative study. [PDF]
Lee CY, Kim SK, Seo HY.
europepmc +1 more source

