Decreased erythrocyte deformability after transfusion and the effects of erythrocyte storage duration. [PDF]
Frank SM +7 more
europepmc +1 more source
All‐Flex Plasma Patch for In Vivo Delivery of Reactive Species
A fully flexible plasma patch enables stable, conformal treatment on complex biological surfaces and enhances transdermal delivery of reactive species. This platform achieves significant tumor suppression in vivo and reveals coordinated regulation of calcium signaling, metabolism, and programmed cell death, providing a promising strategy for safe and ...
Luxiang Zhao +8 more
wiley +1 more source
In silico analysis of the invasion mechanics and invasiveness of the Plasmodium falciparum merozoite. [PDF]
Msosa C, Abdalrahman T, Franz T.
europepmc +1 more source
ABSTRACT Exagamglogene autotemcel (exa‐cel) is a one‐time, ex vivo, CRISPR‐Cas9 gene edited cell therapy approved for patients with transfusion dependent β‐thalassemia (TDT) aged 12–35 years. In a Phase 3 study (CLIMB THAL‐111), exa‐cel treatment resulted in reactivation of fetal hemoglobin and increases in total hemoglobin, leading to transfusion ...
Sujit Sheth +25 more
wiley +1 more source
Therapeutic Applications of Stimuli‐Based Release and Engineering of Extracellular Vesicles
This review summarizes the effects of endogenous and exogenous stimuli, their effects on the natural release of extracellular vesicles, as well as their uptake and release. It also gives an overview of stimuli‐responsive EVs and their therapeutic applications. Extracellular vesicles (EVs), nano‐ to microsized lipid bilayer membrane‐bound particles, are
Gloria Kemunto, Kristen Dellinger
wiley +1 more source
Biomimetic Targeted Drug Delivery for Liver Failure in Abdominal Sepsis: Focus on Autologous Erythrocyte Ghosts. [PDF]
Berikkhanova K +12 more
europepmc +1 more source
Effects of Glutamine and Omega-3 Fatty Acids on Erythrocyte Deformability and Oxidative Damage in Rat Model of Enterocolitis. [PDF]
Cehreli R +3 more
europepmc +1 more source
ABSTRACT Childhood‐onset multisystem Langerhans cell histiocytosis can lead to delayed adult morbidity involving the neurologic, hypothalamic–pituitary, and skeletal systems. Progressive cerebellar dysfunction, chronic pituitary insufficiency, and severe skeletal fragility may emerge years after apparent disease control, underscoring the need for ...
Suhaib Alnahar +4 more
wiley +1 more source
Therapeutic potential of vitamin D in improving antioxidant defense and blood rheology in a rat model of experimental diabetes mellitus. [PDF]
Sakhanberidze N +6 more
europepmc +1 more source
Analysis of ~1000 adults shows cytokine gene variants are more strongly associated with hematological and metabolic traits than fitness classification. IL6 and TNF‐α variants link to iron status and aerobic fitness, with exploratory multi‐locus effects involving IL15. ABSTRACT Genetic variation in cytokine genes may influence cytokine‐related signaling,
Kinga Humińska‐Lisowska +6 more
wiley +1 more source

