Results 171 to 180 of about 5,439 (252)

PD‐1hiCXCR5−CD4+T Peripheral Helper Cells Were Enriched and Potentially Predicted Clinical Response to Etanercept Therapy in Rheumatoid Arthritis

open access: yesMedComm, Volume 7, Issue 8, August 2026.
This study investigated the role of PD‐1hiCXCR5−CD4+ T peripheral helper (Tph) cells in rheumatoid arthritis (RA). Tph cells were increased in the peripheral blood of RA patients and associated with disease activity. Baseline Tph cell levels were linked to the response to etanercept therapy.
Haojie Xu   +10 more
wiley   +1 more source

Host–Guest Interactions Govern Drug Stability and Controlled Therapeutic Release: Based on Metal–Organic Frameworks as Smart Platforms

open access: yesRare Metals, Volume 45, Issue 8, August 2026.
ABSTRACT Due to their exceptional porosity, structural versatility, and modular coordination chemistry, metal–organic frameworks (MOFs) have emerged as versatile platforms for targeted drug delivery. These structures enable fine‐tuning of pore size, surface activity, and framework stability for the encapsulation of a broad range of therapeutics ...
Rui Hua   +9 more
wiley   +1 more source

Advancing Treatment of Degenerative Eye Diseases at the Nanoscale

open access: yesSmart Medicine, Volume 5, Issue 4, August 2026.
Nanotherapeutics possess the potential to overcome longstanding bottlenecks in treating degenerative ophthalmic diseases. With a highly tunable surface chemistry, nanotechnology platforms can be customized to navigate specific anatomical barriers in the eye and target pathways of diseases.
Li Yao Jin   +5 more
wiley   +1 more source

Thrombocytosis and the generation of platelet‐derived microparticles in the pathophysiology of sickle cell disease

open access: yesBritish Journal of Haematology, Volume 209, Issue 2, Page 420-431, August 2026.
Thrombocytosis is associated with an increased production of platelet‐derived microparticles from activated platelets, which contribute to vaso‐occlusion in sickle cell disease by perpetuating the cycle of inflammation, procoagulant state and endothelial dysfunction.
Giao N. Lê   +3 more
wiley   +1 more source

Comparison of the Efficacy and Prognosis of Different Treatment Strategies for Spinal Tuberculosis Patients Undergoing Vertebral Augmentation Surgery by Mistake

open access: yesOrthopaedic Surgery, Volume 18, Issue 8, Page 1631-1640, August 2026.
Based on the clinical characteristics of patients with spinal tuberculosis after percutaneous vertebral augmentation, the corresponding diagnosis and treatment strategies were explored, and clinical data for the differential diagnosis of spinal tuberculosis were provided.
Xiong Xu   +10 more
wiley   +1 more source

Mapping Three Decades of Research on Southeast Asian Ovalocytosis: A Bibliometric Analysis. [PDF]

open access: yesMediterr J Hematol Infect Dis
Helmi MAM   +4 more
europepmc   +1 more source

Brain sparing in fetal growth restriction: The double‐edged sword of fetal hypoxaemia

open access: yesThe Journal of Physiology, Volume 604, Issue 15, Page 6259-6280, 1 August 2026.
Abstract figure legend The double‐edged sword of brain sparing. Fetal hypoxaemia triggers a coordinated adaptive response characterised by redistribution of cardiac output toward essential organs, including the brain, and a reduction in overall metabolic activity to preserve oxygen supply.
Beth J. Allison   +3 more
wiley   +1 more source

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