Results 81 to 90 of about 5,439 (252)

Deformability of Erythrocytes and Oxidative Damage in Alzheimer Disease

Çukurova Üniversitesi Tıp Fakültesi Dergisi, 2012
Purpose: A lowered cerebral perfusion as a consequence of hemodynamic microcirculatory insufficiency is one of the factors underlying in Alzheimer's disease, which is a neurodegenerative disorder leading to progressive cognitive impairment.
Mukerrem Betul Yerer, Sami Aydogan, Emel Koseoglu, Recep Bastug   +3 more
doaj  

Skeleton Binding Protein 1 of Plasmodium berghei Influences Deformability and Cytoskeletal Ultrastructure of Infected Erythrocyte

Shengwu huaxue yu shengwu wuli jinzhan
ObjectiveThe malaria parasites remodel the host erythrocyte structure by exporting parasite proteins that interact with the membrane skeleton proteins of red blood cells (RBCs), facilitating their intracellular survival and pathogenicity.
GUO Xin-Yue, ZHAO Huan-Qi, ZHONG Yan-Xuan, JIANG Ru-Meng, LI Yao-Xian, PAN Lei-Ting, WANG Qian, SHI Xiao-Yu   +7 more
doaj   +1 more source

ANK1 and EPB41 Variants and The Risk of Glucocorticoid‐Induced Osteonecrosis

Arthritis &Rheumatology, EarlyView.
Objective Steroid‐induced osteonecrosis of the femoral head (SONFH) is a refractory skeletal disorder influenced by genetic and environmental factors. However, conclusive pathogenic genetic evidence remains elusive due to the limited exploration of rare damaging variants. In this study, we aimed to identify rare variants associated with SONFH.
Shengbao Chen, Xianmin Zhu, Zhongzhong Chen, Wei Chen, Hussam Alkaissi, Zeng Zhang, Yun Gao, Junhui Yin, Xiangtian Yu, Qiong Fu, Youshui Gao, Zhenzhong Zhu, Qianying Cai, Pengwei Zhang, Weibin Chen, Xin Zhao, Xiaojin Wu, Karel Pacak, Dongxu Jin, Chunde Bao, Zhengping Zhuang, Changqing Zhang   +21 more
wiley   +1 more source

Preliminary Study: Physiological Responses to a Single Bout of Nordic Walking Exercise in Patients with Pre-hypertensive Post-menopausal Women

Experimed
Objective: Cardiovascular diseases are a significant cause of morbidity and mortality globally, particularly among post-menopausal women who face heightened risk. Exercise is recognized for its preventive benefits on cardiovascular health and enhancement
Emine Kılıç Toprak, Ebru Tekin, Yalın Tolga Yaylalı, Fatma Ünver, Ayşegül Çört, Melek Bor-küçükatay   +5 more
doaj   +1 more source

The effects of dyslipidaemia and cholesterol modulation on erythrocyte susceptibility to malaria parasite infection

Malaria Journal, 2019
Background Malaria disease commences when blood-stage parasites, called merozoites, invade human erythrocytes. Whilst the process of invasion is traditionally seen as being entirely merozoite-driven, emerging data suggests erythrocyte biophysical ...
Marion Koch, Jaimini Cegla, Ben Jones, Yuning Lu, Ziad Mallat, Andrew M. Blagborough, Fiona Angrisano, Jake Baum   +7 more
doaj   +1 more source

Harnessing blood clot as a native scaffold for orchestrating tissue repairs and regeneration

BMEMat, EarlyView.
The blood clot, owing to its dynamic composition and unique microenvironment, holds significant yet underappreciated potential for tissue engineering. This review systematically summarizes the pathophysiology of clot formation, the key regulatory factors shaping its microenvironment, and its applications in both pre‐clinical and clinical settings ...
Gao‐peng Dang, Yu‐zhu Wang, Yi‐fei Wang, Que Bai, Jia‐xin Hao, Zhi‐ting Li, Xiao‐qing Cao, Yu Wei, Yue Feng, Ji‐hua Chen, Franklin R. Tay, Rui‐bing Wang, Jun‐ting Gu, Li‐na Niu   +13 more
wiley   +1 more source

Compliant hydrogel cuff coating with real‐time pressure monitoring and antibiofilm capabilities for ventilator‐associated pneumonia prophylaxis

BMEMat, EarlyView.
A soft‐compliant hydrogel cuff coating combines real‐time pressure monitoring with intrinsic antibacterial activity for prophylaxis of ventilator‐associated pneumonia. A flexible pressure‐sensing patch is embedded in the coating to enable wireless dynamic monitoring of endotracheal cuff pressure through Bluetooth.
Jin Chai, Yifu Tan, Jiaheng Liang, Shen Liu, Jiabin Zhao, Shanbo Ma, Chunxin Liu, Minghua Du, Mark Selvan, Xiaopeng Shi, Liqiang Song, Peng Li   +11 more
wiley   +1 more source

Hyperbranched poly‐L‐lysine surface‐engineered bioprosthetic heart valves with anti‐calcification, anti‐infection, and durability

BMEMat, EarlyView.
The challenges of bioprosthetic heart valves (BHV) with respect to calcification, infection, and poor durability are tackled by surface engineering of hyperbranched poly‐L‐lysine (HBPL), providing a translational solution to improve long‐term valve performance.
Pai Peng, Dongchao Qiu, Yongyuan Kang, Qiaoxuan Wang, Xuelong Wang, Boyana Parvanova, Miroslav Karabaliev, Changyou Gao   +7 more
wiley   +1 more source

Electron compensation‐gated nanomotor for immunomodulation and microenvironment remodeling in bacterial pneumonia therapy

BMEMat, EarlyView.
A nanomotor featuring an “electronic lock” via electron compensation in an Au‐Ag alloy ensures therapeutic precision. Near‐infrared light acts as a key, unlocking on‐demand Ag+ release for synergistic bactericidal action and microenvironment remodeling to potently treat bacterial pneumonia. Abstract Bacterial pneumonia treatment is severely hampered by
Chenglong Xue, Xiaoyu Zhao, Yuqian Wang, Lijin Shi, Qi Shuai   +4 more
wiley   +1 more source

The Effect of Chronic Levetiracetam Use on Erythrocyte Deformability

Neurological Sciences and Neurophysiology
Background: The inhibition of carbonic anhydrase (CA) isoenzymes is one of the targets in the development of new antiepileptics. Levetiracetam (LEV) is a new-generation antiepileptic drug frequently used in pediatric patients.
Pinar Kiliçdagi Çanakci, Pelin Şahin, Sevtap Kilinç, Ayşe Meltem Sevgili, Hamit Özyürek   +4 more
doaj   +1 more source