Ubiquitination and degradation of CD47 enhances macrophage phagocytosis of hemolytic erythrocytes [PDF]
iScienceSummary: The destruction of red blood cells by classical complement activation can form erythrocyte ghosts in immune-mediated hemolysis. However, the mechanisms involved in clearing these membrane remnants remain to be elucidated.
Yafen Wang +10 more
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Atomic force microscopy reveals involvement of the cell envelope in biomechanical properties of sickle erythrocytes [PDF]
BMC Biology, 2023 Background Intracellular hemoglobin polymerization has been supposed to be the major determinant for the elevated rigidity/stiffness of sickle erythrocytes from sickle cell anemia (SCA) patients.
Kun Wang +5 more
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Platelet removal from human blood plasma improves detection of extracellular vesicle‐associated miRNA [PDF]
Journal of Extracellular Vesicles, 2023 Human blood plasma prepared by centrifugation contains not only extracellular vesicles (EVs) but also platelets and erythrocyte ghosts (ery‐ghosts).
Jillian W. P. Bracht +6 more
doaj +2 more sources
N-Glycosylation of Band 3 is essential for the binding of Ganoderma lucidum immunomodulatory protein rLZ-8 [PDF]
Applied Microbiology and BiotechnologyFungal immunomodulatory proteins (FIPs) are considered potential therapeutic candidates due to their immunomodulatory and anti-cancer activities. Meanwhile, they are capable of agglutinating mammalian red blood cells in a manner similar to lectins ...
WenTao Diao +6 more
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Direct determination of unbound lipophilic ligands in aqueous solutions [PDF]
Biological Procedures Online, 2004 Due to their hydrophobic nature, lipophilic compounds are always bound to proteins when transported in the organism. The transfer of such compounds between their binding proteins and cells as well as intracellular trafficking is mediated by a very low ...
Bojesen Inge N.
doaj +3 more sources
Red Blood Cell Membrane Vesicles for siRNA Delivery: A Biocompatible Carrier With Passive Tumor Targeting and Prolonged Plasma Residency [PDF]
International Journal of NanomedicineGiulia Della Pelle,1,2 Bostjan Markelc,3 Tim Bozic,3 Jernej Šribar,4 Igor Krizaj,4 Kristina Zagar Soderznik,1 Samo Hudoklin,5,* Mateja Erdani Kreft,5,* Iztok Urbančič,6 Matic Kisovec,7 Marjetka Podobnik,7 Nina Kostevšek1 1Department
Della Pelle G +11 more
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Identification of Exported Plasmodium falciparum Proteins That Bind to the Erythrocyte Cytoskeleton
Microorganisms, 2022 Plasmodium proteins are exported to the erythrocyte cytoplasm to create an environment that supports parasite replication. Although hundreds of proteins are predicted to be exported through Plasmodium export element (PEXEL)-dependent and -independent ...
Bikash Shakya +4 more
doaj +1 more source
Optimization of gradual hemolysis for isolation of hemoglobin from bovine erythrocytes [PDF]
Hemijska Industrija, 2012 In this work, we describe an optimized procedure based on gradual hemolysis for the isolation of hemoglobin derived from bovine slaughterhouse erythrocytes in a membrane bioreactor.
Pravilović Radoslava +6 more
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Erythrocyte G protein as a novel target for malarial chemotherapy. [PDF]
PLoS Medicine, 2006 Malaria remains a serious health problem because resistance develops to all currently used drugs when their parasite targets mutate. Novel antimalarial drug targets are urgently needed to reduce global morbidity and mortality. Our prior results suggested
Sean C Murphy +5 more
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Erythrocytes as Carriers of Therapeutic Enzymes. [PDF]
, 2020 Therapeutic enzymes are administered for the treatment of a wide variety of diseases. They exert their effects through binding with a high affinity and specificity to disease-causing substrates to catalyze their conversion to a non-noxious product, to ...
Bax, BE
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