Albumin‐Bound STING Agonist Reprograms HSPCs to Antitumor Neutrophils Enhancing CD8+ T Cell Immunity
Advanced Science, EarlyView.This study demonstrates that an albumin‐bound STING agonist (Nano ZSA‐51D) reprograms HSPCs to produce antitumor neutrophils with enhanced MHC I–mediated CD8+ T cell activation, thereby sensitizing tumors to α‐PD1 therapy. These findings highlight a strategy to target early hematopoiesis for shaping neutrophil fate and potentiating cancer immunotherapy.
Jinsong Tao +11 more
wiley +1 more source
Non-Invasive Photoacoustic Imaging of In Vivo Mice with Erythrocyte Derived Optical Nanoparticles to Detect CAD/MI. [PDF]
, 2020 Coronary artery disease (CAD) causes mortality and morbidity worldwide. We used near-infrared erythrocyte-derived transducers (NETs), a contrast agent, in combination with a photoacoustic imaging system to identify the locations of atherosclerotic ...
Anvari, Bahman +9 more
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Aminoglycoside-Induced Phosphatidylserine Externalization in Sensory Hair Cells Is Regionally Restricted, Rapid, and Reversible [PDF]
, 2008 The aminophospholipid phosphatidylserine (PS) is normally restricted to the inner leaflet of the plasma membrane. During certain cellular processes, including apoptosis, PS translocates to the outer leaflet and can be labeled with externally applied ...
Gale, Jonathan E +4 more
core +1 more source
Gastric hemorrhage due to high pungency food?
JPGN Reports, EarlyView.Abstract We present a case of a 9‐year‐old patient who presented with hematemesis after consuming crisps with a high pungency (the so‐called ghost peppers). Blood loss resulted in a significant decrease in hemoglobin and for this reason a gastroduodenoscopy was performed.
Rachel J. van der Pol +2 more
wiley +1 more source
Spin Label Studies of the Hemoglobin–Membrane Interaction During Sickle Hemoglobin Polymerization [PDF]
, 2010 An enhanced hemoglobin–membrane association has been previously documented in sickle cell anemia. However, it is not known how this interaction is modified during the hemoglobin S polymerization process.
Falcón Dieguez, Jose +3 more
core +1 more source
Erythrocyte ‘Feierzeit’ reaction: Novel filamentous and vesicular response to n‐butyl acetate
Journal of Microscopy, EarlyView.Abstract Human erythrocytes (red blood cells; RBCs) undergo spontaneous disassembly after several hours of exposure to n‐butyl acetate (nBA). Images of the morphological changes were captured in time‐lapse sequences using differential interference contrast (DIC) light microscopy.
Philip W. Kuchel
wiley +1 more source
Softlithography in Chemical Sensing – Analytes from Molecules to Cells
Sensors, 2005 Imprinting is a flexible and straightforward technique to generate selective sensormaterials e.g. for mass-sensitive detection. Inherently, the strategy suits both molecularanalytes and entire micro organisms or cells. Imprinted polyurethanes e.g.
Anton Leidl +5 more
doaj +1 more source
Grape epicatechin conjugates prevent erythrocyte membrane protein oxidation [PDF]
, 2012 Epicatechin conjugates obtained from grape have shown antioxidant activity in various systems. However, how these conjugates exert their antioxidant benefits has not been widely studied.
Martínez Ocaña, Verónica +4 more
core +1 more source
Immunology, Volume 177, Issue 4, Page 784-797, April 2026.This study investigates the role of MyD88 in dendritic cells (DCs) and T cells during experimental autoimmune encephalomyelitis (EAE). We found that MyD88 is highly expressed in DCs and CD4+ T cells in people with multiple sclerosis, and its deficiency impairs DC maturation, reduces pro‐inflammatory cytokine production, weakens DC–T cell interactions ...
Wen Si +4 more
wiley +1 more source
THE SUBSTANTIATION OF LOCAL TREATMENT OF PURULENT WOUNDS BY PHARMACOCYTES WITH DIOXYDIN
Сеченовский вестник, 2017 The article discusses the topical purulent wounds treatment with pharmacocytes and dioxidin. MIC, MIC50 and MIC90 of dioxidin were tested on 77 strains, isolated from the purulent wounds of various localizations.
S. Fedzianin
doaj