Results 61 to 70 of about 4,783 (213)

Albumin‐Bound STING Agonist Reprograms HSPCs to Antitumor Neutrophils Enhancing CD8+ T Cell Immunity

Advanced Science, Volume 13, Issue 29, 22 May 2026.
This study demonstrates that an albumin‐bound STING agonist (Nano ZSA‐51D) reprograms HSPCs to produce antitumor neutrophils with enhanced MHC I–mediated CD8+ T cell activation, thereby sensitizing tumors to α‐PD1 therapy. These findings highlight a strategy to target early hematopoiesis for shaping neutrophil fate and potentiating cancer immunotherapy.
Jinsong Tao, Hong‐Yi Zhao, Chengyi Li, Hanning Wen, Fang Ke, Qiuxia Li, Miao He, Bo Wen, Zhongwei Liu, Kai Sun, Wei Gao, Duxin Sun   +11 more
wiley   +1 more source

Phospholipid transfer activities in toad oocytes and developing embryos.

Journal of Lipid Research, 1986
The role of lipid transfer proteins during plasma membrane biogenesis was explored. Developing amphibia embryos were used because during their growth an active plasma membrane biosynthesis occurs together with negligible mitochondrial and endoplasmic ...
A Rusiñol, R A Salomón, B Bloj
doaj   +1 more source

Gastric hemorrhage due to high pungency food?

JPGN Reports, Volume 7, Issue 2, Page 278-280, May 2026.
Abstract We present a case of a 9‐year‐old patient who presented with hematemesis after consuming crisps with a high pungency (the so‐called ghost peppers). Blood loss resulted in a significant decrease in hemoglobin and for this reason a gastroduodenoscopy was performed.
Rachel J. van der Pol, Anemone van den Berg, Wendy L. van der Woerd   +2 more
wiley   +1 more source

Carrier screening in the reproductive setting—Are there medical implications for the heterozygote?—A guide for clinicians

Pregnancy, Volume 2, Issue 3, May 2026.
Abstract Carrier screening for genetic conditions performed preconception or during pregnancy allows identification of fetal risk for inherited autosomal recessive and X‐linked conditions. The goal is to identify at‐risk patients/couples and offer them reproductive options such as preimplantation genetic diagnosis, prenatal testing, or targeted newborn
Emily B. Rosenfeld, Nicole Kasatkin, Bi Liu Yu, Milen Velinov, Justin S. Brandt, Elena Ashkinadze   +5 more
wiley   +1 more source

Vaccination accelerates hepatic erythroblastosis induced by blood-stage malaria

Malaria Journal, 2020
Background Vaccination induces survival of otherwise lethal blood-stage infections of the experimental malaria Plasmodium chabaudi. Blood-stage malaria induces extramedullary erythropoiesis in the liver.
Denis Delic, Frank Wunderlich, Saleh Al-Quraishy, Abdel-Azeem S. Abdel-Baki, Mohamed A. Dkhil, Marcos J. Araúzo-Bravo   +5 more
doaj   +1 more source

Quantitative introduction of a given macromolecule into cells by fusion with erythrocyte ghosts using a fluorescence activated cell sorter.

, 1978
FITC-conjugated bovine serum albumin (FITC-BSA) molecules were quantitatively introduced into human erythrocyte ghosts by gradual hemolysis. When the ghosts and L cells were fused with UV-inactivated HVJ (Sendai virus), FITC-BSA was introduced into the ...
T Uchida, M Yamaizumi, E Mekada, Y Okada
core   +1 more source

Improved bilirubin reduction with therapeutic plasma exchange and haemoperfusion in a dog with immune‐mediated haemolytic anaemia

Veterinary Record Case Reports, Volume 14, Issue 2, May 2026.
Abstract A 6‐year‐old spayed female Golden Retriever mix was diagnosed with immune‐mediated haemolytic anaemia. Initial treatments included immunosuppression and blood transfusions. With acute mentation decline and rapid increase in serum bilirubin, therapeutic plasma exchange (TPE) was initiated.
Natasha S. Yeh, Kay Drake, Michael T. Kato   +2 more
wiley   +1 more source

Normal erythrocyte calpain I activity on membrane proteins under near-physiological conditions in patients with essential hypertension

São Paulo Medical Journal, 2002
CONTEXT: It has been reported that the equilibrium between the erythrocyte protease calpain I and its physiological inhibitor calpastatin is disrupted in patients with essential hypertension. OBJECTIVE: To investigate the activity of non-purified calpain
Tereza Maria Dantas de Medeiros, Katia Coelho Ortega, Décio Mion Júnior, Kimiyo Nonoyama, Orlando Cesar de Oliveira Barretto   +4 more
doaj   +1 more source

Effects of calcium and lead on potassium permeability of human erythrocyte ghosts

, 1971
K+ efflux from reconstituted erythrocyte ghosts was induced by Pb2+ or by Ca2+ in the presence or absence of F− or iodoacetic acid plus adenosine. Oligomycin completely inhibited Ca2+-induced K+ loss and partially inhibited loss caused by maximally ...
Passow, H., Riordan, J.
core   +1 more source

Spleen‐Targeting Biomimetic Hybrid Nanocarriers for Systemic Immune Reprogramming in Colitis: RBC Membrane Vesicle‐Fused Lipid Nanoparticles

Advanced Functional Materials, Volume 36, Issue 31, 16 April 2026.
A spleen‐targeting hybrid nanoplatform (RBCMV‐LNP‐RP) harnessing erythrophagocytosis mimics senescent red blood cell clearance to achieve spleen‐specific delivery of rapamycin. This biomimetic system enables selective accumulation in splenic macrophages, orchestrating systemic immune reprogramming and promoting mucosal healing in an inflammatory bowel ...
Jun Kwon, Hee Su Sohn, Jong Sang Yoon, So Won Jeon, Hee Gyeong Ko, Min‐Ho Kang, Jisun Lee, Jae‐Hwan Nam, Louis T. Merriam, Edy Y. Kim, Han Young Kim   +10 more
wiley   +1 more source