Results 131 to 140 of about 24,129 (300)

Mechanism‐Informed Machine Learning Enables Discovery of Oncolytic Peptides for Cancer Immunotherapy

Advanced Science, EarlyView.
MISPOP integrates ensemble learning with membrane‐active physicochemical priors to identify Dermaseptin‐S9, a natural oncolytic peptide that disrupts tumor membranes, triggers immunogenic cell death, and shows strong antitumor activity. The study illustrates a mechanism‐informed route from peptide sequence data to cancer immunotherapy leads.
Wen Zhang, Shengxin Lu, Guangyong Zheng, Shensuo Li, Hongyu Chen, Mei Hong, Xiangru Zhou, Ruotian Tang, Ye Wu, Weidong Zhang, Dong Lu, Xin Luan   +11 more
wiley   +1 more source

Red cell distribution width-to-platelet ratio (RPR) as a predictor of prolonged stay at hospital for COVID-19 inpatients

Future Science OA
Aims/Background We looked at novel hematological composites like the neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, monocyte-to-lymphocyte ratio, red cell distribution width-to-lymphocyte ratio, red cell distribution width-to-platelet ...
Martha Fors, Santiago J. Ballaz
doaj   +1 more source

Assessment of Erythrocyte Osmotic Fragility and Its Determinants, and Comparison of Hematological Indices Among Type 2 Diabetes Mellitus Patients on Follow-Up at Jimma Medical Center, Southwest Ethiopia

Zenebe Tujara,1 Wondu Reta,2 Eyasu Tadesse,2 Ifa Dereje,1 Mekonnen Tesfa1 1Department of Medicine, College of Health sciences, Salale University, Fiche, Oromia, Ethiopia; 2Department of Biomedical Sciences, Institute of Health, Jimma University, Jimma ...
Tesfa M, Reta W, Tadesse E, Dereje I, Tujara Z   +4 more
core  

Orchestrated Engineered Polyphenol‐Peptide Condensates Coupled With β‐GP Reverses Diabetic Osteoporosis by Remodeling Mitophagy

Advanced Science, EarlyView.
A multifunctional β‐GP@EGCG‐E7 nanoplatform is engineered by polyphenol–peptide condensation and phosphate loading. Bone‐targeted delivery, antioxidant and anti‐inflammatory activity, and mitophagy restoration are integrated in one system, enabling protection of osteoblasts and endothelial cells and promoting bone regeneration under diabetic ...
Xiuyun Xu, Meiqin Zhang, Ting Wu, Erfan Wei, Andrei Y. Hancharou, Zeying Wang, Zijuan Wang, Letian Lv, Likun Wu, Xingtong Pan, Qiyue Zhu, Xinyi Dong, Hao Liu, Yongsheng Zhou   +13 more
wiley   +1 more source

ERYTHROCYTE INDICES IN NORMAL ONE-HUMPED CAMEL: EFFECTS OF SEX, AGE IN MALES AND LACTATION AND/OR PREGNANCY IN FEMALES [PDF]

, 1992
Seven erythrocyte indices were studied in 56 clinically healthy one-humped camels in summer. Twenty-eight of these were males divided into four groups of seven each: upto 4 years old, 5 to 6 years, 6 to 7 years, and above 7 years.
& M N Chaudhry, M A Majeed, Anas Sarwar, I R Khan   +3 more
core  

A new approach to define acceptance limits for hematology in external quality assessment schemes.

, 2017
<p><b>BACKGROUND: </b>A study performed in 2007 comparing the evaluation procedures used in European external quality assessment schemes (EQAS) for hemoglobin and leukocyte concentrations showed that acceptance criteria vary widely. For
I. Plum, Mohamed Rida Soumali, Marjan Van Blerk, D. Kesseler, Gabriela Gutierrez, G. Gutierrez, Ana Paula Favia, Barbara de la Salle, Wim Coucke, A. Akharif, Anne Guyard, M.Rida Soumali, A. Guyard, Abdelhadi Akharif, B. de la Salle, M. Van Blerk, S. Albarède, W. Coucke, Inger Plum, A.Paula Favia, Stéphanie Albarède, Dagmar Kesseler   +21 more
core   +1 more source

Lactoferrin Deficiency During Lactation Causes Adult Obesity‐Related Metabolic Disease Through Persistent Adipose Dysfunction Driven by Impaired Adipocyte Development

Advanced Science, EarlyView.
Lactational lactoferrin deficiency exerts lasting effects on epididymal adipose tissue development from lactation into adulthood: it impairs adipocyte hyperplasia and induces pathological hypertrophy, resulting in lower body weight yet exacerbated metabolic dysfunction under a high‐fat diet in adulthood.
Qin An, Yunxia Zou, Wenli Wang, Zhimei Cheng, Zhuoxing Zhang, Ruwei Liu, Xiong Wang, Kunlun Huang, Fangrong Ding, Yunping Dai, Qingyong Meng, Yali Zhang   +11 more
wiley   +1 more source

Multi‐Axis Stretchable Zippers for Personalized Wound Healing

Advanced Science, EarlyView.
Multi‐axis stretchable zippers can adapt to complex wound morphologies and enable personalized wound treatment through programmable contraction. This morphological matching strategy helps accelerate wound closure, improve blood perfusion, promote epithelial regeneration, and enhance collagen remodeling, pioneering new directions for personalized and ...
Siyuan Cai, Guang Yao, Zijian Chen, Shiqi Zhou, Peisi Li, Liheng Lin, Huake Yang, Ziyi Zhou, Linbo Jin, Xingyi Gan, Chenzheng Zhou, Zhen Cai, Taisong Pan, Min Gao, Dongli Fan, Yuan Lin, Yiming Zhang   +16 more
wiley   +1 more source

The effects of propofol and memantine on erythrocyte deformability

, 2014
Arslan, Mustafa/0000-0003-4882-5063; PAMPAL, HASAN KUTLUK/0000-0003-4664-391XObjective: Propofol is an intravenous general anesthetic with a primary hypnotic effect.
Unal, Y., Alkan, M., Pampal, H. K., Arslan, M., PAMPAL, HASAN KUTLUK, Emik, U., Alkan, METİN, Comu, F. M., ARSLAN, MUSTAFA   +8 more
core   +1 more source

Targeting ANGPTL3 and IL‐33/ST2 Ameliorates Diabetic Kidney Disease by Reducing Lipotoxicity, Alleviating Inflammation and Inhibiting Fibrosis

Advanced Science, EarlyView.
Dual targeting of ANGPTL3 and IL‐33/ST2 attenuates diabetic kidney disease by reprogramming lipid–inflammatory crosstalk. This strategy reduces renal lipotoxicity, suppresses inflammatory activation, and limits fibrotic remodeling, thereby preserving kidney structure and function and highlighting a mechanism‐guided therapeutic approach for metabolic ...
Zhuojin Li, Zhonglian Cao, Rongrui Zhou, Xu Cheng, Xiaozhi Hu, Shuwen Xu, Zihan Dou, Ling Du, Dianwen Ju   +8 more
wiley   +1 more source