Results 251 to 260 of about 45,820 (279)

Mannose‐Modified Cationic Liposome‐Based mRNA Therapeutics for Improved Triple‐Negative Breast Cancer Immunotherapy

open access: yesAdvanced NanoBiomed Research, EarlyView.
Schematic illustration of mTEM8‐loaded cationic liposome (cLipo‐Man/mTEM8) therapeutics for improved triple‐negative breast cancer immunotherapy. Despite triple‐negative breast cancer (TNBC) is the most heterogeneous and aggressive subtype of breast cancer, immunotherapy is emerging as a promising therapy.
Kexin Deng   +10 more
wiley   +1 more source

Loss of Tripartite Motif–Containing Protein 21 and UVB‐Induced Systemic Inflammation by Regulating DNA‐Sensing Pathways

open access: yesArthritis &Rheumatology, EarlyView.
Objective Patients with systemic lupus erythematosus (SLE) experience photosensitivity, with exposure to UVB light driving lupus flares and triggering symptoms like joint pain, fatigue, and cutaneous lesions. Although the mechanism(s) linking UVB exposure to systemic effects are unclear, type I interferons (IFNs) are known to play a role.
Gantsetseg Tumurkhuu   +17 more
wiley   +1 more source

Comparative Effectiveness of Abatacept Versus Adalimumab in Shared Epitope Positive and Negative Patients With Rheumatoid Arthritis

open access: yesArthritis &Rheumatology, EarlyView.
Objective The effect of the shared epitope (SE) and valine at position 11 (Val11) of HLA–DRB1 on the activation of CD4+ T cells is expected to be diminished by abatacept, a costimulation blocker. However, published evidence on the value of genetic stratification for abatacept treatment is conflicting. We aimed to compare the difference in effectiveness
Chuan Fu Yap   +14 more
wiley   +1 more source

Late‐Onset Spondyloarthritis Presenting as Glucocorticoid‐Resistant Polymyalgia Rheumatica: A Hitherto Underappreciated Entity in Which Tumor Necrosis Factor or Interleukin ‐17 Blockade May Have a Therapeutic Role

open access: yesArthritis &Rheumatology, EarlyView.
Objective Polymyalgia rheumatica (PMR) is an age‐related inflammatory disease with shoulder/hip girdle involvement. Magnetic resonance imaging (MRI) reveals extracapsular/entheseal soft tissue involvement in both PMR and spondyloarthritis (SpA), with sacroiliac joint and perientheseal spinal bone marrow edema (BME) being characteristic of SpA ...
Kerem Abacar   +12 more
wiley   +1 more source

Predictive value of hematological parameters for IVF success: a retrospective analysis. [PDF]

open access: yesFront Reprod Health
Tulucu Kalkan F   +6 more
europepmc   +1 more source

Case‐Based Immunology: B Cells and Systemic Sclerosis Interstitial Lung Disease

open access: yesArthritis &Rheumatology, EarlyView.
Interstitial lung disease (ILD) is an important complication of systemic sclerosis (SSc), with high mortality and morbidity. Recent clinical studies in SSc‐ILD have led to US Food and Drug Administration–approved therapies in SSc‐ILD. Importantly, evidence from these studies has been extrapolated to guide management of ILDs of other systemic autoimmune
Nina Goldman   +2 more
wiley   +1 more source

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