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Plasmodium knowlesi can adapt to infect Duffy-negative erythrocytes.

Blood
Zinga M, Ibrahim A, Mohring F, Chainarin S, Jonsdottir TK, Ngernna S, Amabilino-Perez B, Pholcharee T, Turkiewicz A, Campino S, Clark TG, Miao J, Cui L, Roobsoong W, Sattabongkot J, Moon RW, Nguitragool W.   +16 more
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Plasmodium falciparum: Protease inhibitors and inhibition of erythrocyte invasion

Experimental Parasitology, 1986
Invasion of human red blood cells by Plasmodium falciparum is inhibited by the protease inhibitors, leupeptin and chymostatin. The efficacy of chymostatin was reduced if the cells were first treated with chymotrypsin. On the other hand, exposure of fresh cells to the supernatant from a synchronous culture at the reinvasion stage showed no such effect ...
A R Dluzewski, K Rangachari, R J M Wilson   +2 more
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Invasion of Erythrocytes by Malaria Merozoites

Science, 1975
An electro-optical system was developed to record microscope images with high resolution at low light intensities. The system was used to study the invasion of erythrocytes by malaria merozoites. Invasion consists of attachment of the anterior end of the parasite to the erythrocyte, deformation of the erythrocyte, and entry of the parasite by ...
J A, Dvorak, L H, Miller, W C, Whitehouse, T, Shiroishi   +3 more
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Malaria parasites and erythrocyte invasion

Biochemical Society Transactions, 1994
21 Flinn, H. M. (1992) Ph.L). Thesis, University of London, London 22 Flinn, H. M., Rangarajan, D. and Smith, L). F. (1 994) Mol. Hiochem. Parasitol., in the press 23 Guss, H., Uhlen, M., Nilsson, B., Lindberg, M., Sjoqvist, I. and Sjodahl, I. (1984) Eur. J. Biochem. 138, 4 13-420 24 lihlen, M.. Cuss, H., Nilsson, H.. Gatenbeck, S., Philipson, I,.
A A, Holder, M J, Blackman, M, Borre, P A, Burghaus, J A, Chappel, J K, Keen, I T, Ling, S A, Ogun, C A, Owen, K A, Sinha   +9 more
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Plasmodium falciparum: Assay of invasion of erythrocytes

Experimental Parasitology, 1981
Abstract A method for quantitatively assaying Plasmodium falciparum merozoite invasion of particular erythrocytes is described. Erythrocytes were labeled with fluorescein isothiocyanate which did not affect parasite entry or growth, to distinguish them from uninfected erythrocytes in the original parasitized cell population. Parasites were detectable
G, Lamont, A, Saul, C, Kidson
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Malaria invasion of human erythrocytes

Parasitology Today, 1987
The invasion of human red blood cells (RBC) by plosmodiol merozoites is a key event during malaria infection, and the inhibition o f invasion is regarded as a crucial goal of malaria vaccine development. For Plasmodium falciparum it has been suggested that the red cell sialoglycoproteins, glycophorins A, B and C, are receptors for invasion and that O ...
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Assay of Erythrocyte Components as Inhibitors of Plasmodium Falciparum Merozoite Invasion of Erythrocytes

The American Journal of Tropical Medicine and Hygiene, 1983
Three red blood cell membrane fractions (Band 3, macromolecules exhibiting I antigenic determinants, and a delipidated glycoprotein fraction) were separated from red blood cell membranes and tested for their ability to inhibit penetration of red blood cells by Plasmodium falciparum merozoites in an in vitro inhibition assay.
S, Schulman, J D, Oppenheim, J P, Vanderberg   +2 more
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Erythrocytic schizogony and invasion of Plasmodium vivax in vitro

International Journal for Parasitology, 1988
Abstract Several isolates of Plasmodium vivax were cultured in vitro using a culture procedure specially modified to enhance the reinvasion rate of parasites. Between 30 and 40 h after start of the culture with blood containing mainly ringforms and young trophozoites, parasites were concentrated on Nycodenz gradients.
B, Mons, J J, Croon, W, van der Star, H J, van der Kaay   +3 more
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Erythrocyte sialoglycoproteins and Plasmodium falciparum invasion

Transactions of the Royal Society of Tropical Medicine and Hygiene, 1983
Human erythrocytes with a deficiency in glycophorin A (En(a-) cells) and glycophorin B (S-s-U- and S-s-U+ cells) show significant resistance in vitro to invasion by Plasmodium falciparum merozoites. Treatment of normal erythrocytes with trypsin and chymotrypsin also reduced invasion.
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Staurosporine Inhibits Invasion of Erythrocytes by Malarial Merozoites

Experimental Parasitology, 1994
Staurosporine, a protein kinase inhibitor, inhibits the invasion of rhesus by Plasmodium knowlesi merozoites with an IC50 of 250 nM. The drug exerts its effects primarily on the merozoite, with little or no effect on the erythrocyte. Okadaic acid, an inhibitor of protein phosphatases, can partially abrogate the inhibitory effects of staurosporine ...
G E, Ward, H, Fujioka, M, Aikawa, L H, Miller   +3 more
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