Results 241 to 250 of about 1,239,207 (305)

Acid‐Responsive Nanobot‐Integrated Core‐Shell Microneedles Reprogram the Degenerative Annulus Fibrosus Microenvironment Through Epigenetic Suppression of Ferroptosis

open access: yesAdvanced Science, EarlyView.
An acid‐responsive core‐shell microneedle system normalizes the degenerative annulus fibrosus microenvironment by consuming pathological H+, generating O2, and providing NIR‐amplified redox buffering. Mechanistically, it epigenetically suppresses ferroptosis via DNMT3A‐dependent methylation of the ATF3 promoter, relieving ATF3‐mediated repression of ...
Lu Tan   +7 more
wiley   +1 more source

Isocyanate‐Modified Melatplatin(IV) Enhances Antitumor Efficacy via TCF4/COL6A3‐Mediated Extracellular Matrix Remodeling and cGAS‐STING Pathway Activation in Bladder Cancer

open access: yesAdvanced Science, EarlyView.
A series of melatonin‐conjugated platinum(IV) prodrugs was functionalized with isocyanate chains (compounds 5‒12). MP‐12C (compound 11) was identified as the lead candidate, with optimal potency and safety. MP‐12C exhibited greater efficacy than cisplatin by increasing intracellular uptake, reshaping the extracellular matrix, activating the cGAS‐STING ...
Linhui Wang   +18 more
wiley   +1 more source

Antibodies to specific domains of <i>Plasmodium falciparum</i> erythrocyte membrane protein-1 and its relationship with protection from severe malarial anemia: A prospective study among Ghanaian children. [PDF]

open access: yesHealth Sci Rep
Nkansah C   +18 more
europepmc   +1 more source

Erythrocyte membrane protein 3 (EMAP3) is exposed on the surface of the Plasmodium berghei infected red blood cell

open access: yes
Hernandez S   +10 more
europepmc   +1 more source
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Erythrocyte membranes: Effects of sonication

Biochimica et Biophysica Acta (BBA) - Biomembranes, 1968
Abstract Chromatographic, ultracentrifugal and electron-microscopic studies show that sonication of red blood cell membranes breaks these membranes into small vesicles and linear fragments having intact unit membrane structures. These fragments are from 100 to 600 A in size and do not sediment under conditions usually used to define solubility.
S A, Rosenberg, J R, McIntosh
openaire   +2 more sources

The Structure of the erythrocyte membrane

Experientia, 1969
Neuere Resultate physikochemischer und chemischer Untersuchungen an Erythrozytenmembranen und Stromaproteinen, welche zum Teil im Widerspruch zur «unit-membrane»-Theorie stehen, werden diskutiert. Die Folgerungen aus diesen Ergebnissen werden anhand von vier kurzliche vorgeschlagenen Strukturmodellen dargelegt, wobei folgende gemeinsame Gesichtspunkte ...
openaire   +2 more sources

A radioactive label for the erythrocyte membrane

Biochimica et Biophysica Acta (BBA) - Biomembranes, 1971
Abstract A new radioactive reagent, diazotized [ 131 I] diiodosulfanilic acid, which binds specifically to protein groups of the erythrocyte membrane, is described. The labeling reaction and some of the effects of varying amounts of the bound isotope on red cell structure and function have been described.
D A, Sears, C F, Reed, R W, Helmkamp
openaire   +2 more sources

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